224 results
Investigate the hypothesis that children with ADHD have difficulty with the allocation of visio-spatial attention related to an inability to control posterior alpha. A paradigm will be used in which the aim is to address covert attention as similar…
The objective of the study is to investigate effects of training on insulin resistance (IR), chronic heart failure (CHF) and cognition of resthome residents.
An online testing approach to assess cognitive problems associated with cancer and cancer treatment.
The aim of the proposed project is to develop a user-friendly and standardized online neuropsychological test battery. It will be a concise test, measuring those domains which have proven to be most sensitive to the adverse effects of chemo- and…
- to evaluate the safety and tolerability of a single oral dose of SCH 900229 administered to healthy adult volunteers- to characterize the pharmacokinetic (PK) profile of SCH 900229 in plasma of healthy adult volunteers after a single oral dose- to…
To study whether the administration of oxytocin leads to stronger empathic responses on 3 different empathy-related tasks compared to a placebo.
This study aims to determine the effects of acute coffee consumption compared to consumption of decaffeinated coffee on subjective fatigue and vitality ratings, neuropsychological performance and brain activity during working memory and learning…
The primary objective of this study is to provide access to SPD503 following participation in SPD503-315 or SPD503-316. The primary outcome of this study is to evaluate the long-term safety of SPD503. The evaluation of safety will be based on the…
The primary objective of this study is to evaluate the long-term maintenance of efficacy of SPD503 in childrenand adolescents (6-17 years) with attention-deficit/hyperactivity disorder (ADHD) who respond to an initial open-label,short-term treatment…
To demonstrate the extent to which an intervention that combines treadmill training augmented by virtual reality (TT+VR) reduces fall risk, improves mobility and enhances cognitive function in a diverse group of older adults, compared to a treadmill…
The aim of this protocol is to invite the NeuroIMAGE cohort once more for a follow-up investigation and collect phenotypical, cognitive, and MRI data. This design offers the opportunity to examine by means of longitudinal phenotypic, cognitive, and…
Objectives of the study: Project 1 - To assess early adaptive deficits in a multicentre cohort of mild to moderate TBI patients and their relation to outcome. Project 2 - Early intervention study of Cognitive Behavioural Therapy (CBT) to assess…
In this study, three main hypotheses are tested. The first hypothesis focuses on the expectation that an intervention aimed at training cognitive components of social competence affect the level of social competence and well-being of adolescents…
The goal of this study is to determine if off-pump CABG surgery is associated with better cerebral tissue oxygenation when compared with on-pump CABG. In addition, we would like to compare the results of two different monitors of brain tissue…
We will investigate the changes in mental performance using a validated computerize test battery of neuropsychological tests just before, three montns and one year after living kidney donation. Using visual and auditory inormation stimuli, these…
The current study aims to further our understanding of the relationship between baseline measures - such as impulsivity, working memory and social support - and the effects of enhancing dopamine (via methylphenidate administration) across a wide…
The principal objective of this study will be to critically evaluate if the fMRI-neurofeedback training is successful in reducing ADHD symptoms and improving cognitive functioning. Thus, the first goal is to show that ADHD patients are able to…
This pilot study is set up to test the feasibility of the BrainGame Brian program in a small subsample of very preterm children at 8 to 10 years of age. Evidence that the program is feasible and differences in EF between pre-training assessments and…
The objective is to examine the physical fitness of children with moderate to severe intellectual disability.
Primary objectives:This is a pilot study. The main objective is to investigate the feasibility of the study. This feasibility will be tested by estimating: 1. the percentage of inclusion, 2. the incidence of behavioural changes for which the GP is…
- To assess the safety and tolerability of escalating single and multiple IV doses of SAR228810 in AD patients- To evaluate the pharmacokinetic properties of SAR228810 in plasma and CSF after escalating single and multiple IV doses of SAR228810 in…