7 results
The primary outcome of this study is to assess whether the maximum ICDSC score achieved each day is related to PK parameters of haloperidol in ICU patients with delirium. Secondary outcomes: - To characterize the association between daily…
To determine an increased risk of falling during a delirium
Primary objective1. To examine the association between the use of haloperidol and the acute changes in serum glucose and QT interval in elderly patients undergoing orthopaedic surgery.Secondary objectives1.To examine the association between the use…
Primary objective 1. To examine the association between the use of haloperidol and the acute changes in fastening serum glucose and QT interval in elderly patients undergoing surgery. Secondary objectives 1.To examine the association between the use…
to reduce ptsd symptoms and psychological suffering in general, and to improve quality of life
Primary objective:Plasma levels of clonidine, in order to describe pharmacokinetic and pharmacodynamic properties of intravenous clonidine in critically ill ventilated ICU patients.Secondary objectives are: * to evaluate the effect of a 3-hr loading…
To obtain a nonlinear mixed effects model (NONMEM) describing the population pharmacokinetics of haloperidol in the central (CSF) and peripheral compartment after oral and intravenous injection.