14 results
The aims of this research are to estimate the efficacy of a relatively brief group CBT for bipolar disorders, by following the level of mood symptoms over time, and by assessing whether changes in dysfunctional attitudes and sense of mastery over…
Primary objective: evaluation of feasibility of a pilot intervention by measuring adherence to the training program and evaluation of the different aspects by the participants Secondary objective: measuring possible beneficial effects on all domains…
As there are limited data on how to improve outcomes for those patients who do not benefit sufficiently from the availabletreatments, this study aims to compare MBCT to TAU as an adjunctive treatment to reduce depressive symptoms in patientswith…
We expect Collaborative Care to have a positive effect on functioning, amount and severity of symptoms, quality of life, costs, mastery, attitude to pharmacotherapy, and satisfaction with care. If effect of this intervention can be demonstrated we…
The main purpose of the study is to investigate whether the transdermal patch system HP-3070 shows blood concentrations of asenapine that make this route of administration suitable for clinical use. The transdermal route of administration is likely…
To compare the effect of amiloride on lithium-induced Nephrogenic Diabetes Insipidus with the effect of hydrochlorothiazide, measured as urine volume and maximal urine osmolality.
The primary objective of the study is to investigate whether CRT reduces subjective cognitive symptoms. It is hypothesized that there is a significant improvement in subjective cognitive symptoms as measured by the Cognitive Failure Questionnaire (…
Objective: We want to determine the effectiveness of rTMS in patients with bipolar depression who did not respond to two or more adequately dosed medication trials, using an adequately powered pragmatic RCT. We hypothesize that active rTMS, compared…
Primary Objective: To confirm that the lithium headcoil is capable of measuring lithium signals related to clinical doses in the brains of BD patients (MDR, art 82), and then to establish the correlation of neuroimaging data of lithium…
The primary objective of this trial is to investigate the effects of probiotics, as compared to placebo, when given in addition to antipsychotic/mood stabilizing medication to a selected patient sample. Our aim will be to lower symptom severity as…
Our study aims to assess the effectiveness of a brief Imagery-focussed Cognitive Therapy (ImCT) compared to psychoeducation, regarded as treatment as usual for this patient population, in patients suffering from Bipolar Disorder. ImCT was…
The aim of the study is to investigate the effectiveness of schema therapy in older adults with BPD.
Primary objective: to investigate the effect of amiloride on urine volume and urinary concentrating ability in patients on chronic lithium therapy suffering from polyuria.We hypothesize that amiloride therapy will improve urinary concentating…
Objective: The primary objective is to examine whether EMDR therapy has mood-stabilizing effects in traumatized patients with mild depressive and/or manic symptoms. The secondary objective is to examine the hypothesis that EMDR is an effective and…