28 results
The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…
Primary Objective: To investigate the behavioral effects of controlled discontinuation as well as the feasibility of discontinuing currently ongoing treatment with risperidone in children and adolescents with behavioral problems who have used…
The aim of this (pilot) study is to investigate if stress affects memory and attention skills by impacting the dopamine and noradrenalinesystem.
To assess the effects of Cognitive Behavioral Therapy (CBT) in pregnant women with symptoms of anxiety or depression on the child*s behavioral/emotional problems. In addition, we aim to study its effects on the child*s development, maternal mental…
The primary objective is to investigate brain functioning during (reversal) fear conditioning and reward/punishment conditions during different experimental conditions. Secondary objectives include investigation of connectivity between brain…
The aim of study I is to compare the two working memory interventions, Cogmed and the intervention developed by the Bascule, in a sample of 100 children with ADHD and working memory deficits, aged between 8 and 12 years old. Effects on working…
The primary objective of this study is to test the hypothesis that risperidone given orally in a dose of 0.25 - 3.0 mg/d depending on body weight (eq. to approximately 0.01 - 0.04 mg/kg/d) for 12 weeks is superior to placebo in reducing disruptive…
The primary objective is to test the hypothesis that, after at least 15 weeks of daily administration (4 for titration, 7 of relatively stable dose, 4 at fixed doses; Study Period II), risperidone given orally in a dose of 0.25 - 3.0 mg/d depending…
See page 9Primary Objective:The primary objective of this study is to explore the relationship between MPH and academic activity and the mediating roles of ADHD behaviours, cognitive deficits and motivational deficits in this relationship. Therefore…
To evaluate the effects of tDCS on modulating and stydying frontal brain asymmetry.
1. Randomised controlled determination of the influence of foods on the behaviour of a heterogeneous not-selected group primary school children, during the first two months of the trial. 2. Determination of an IgG or IgE-mediated respons to foods,…
To assess the effects of Cognitive Behavioral Therapy (CBT) in pregnant women with symptoms of anxiety or depression on the child*s behavioral/emotional problems. In addition, we aim to study its effects on the child*s development, maternal mental…
The aim of the present double blind cross-over sham controlled study is to study the functional role of the left and right frontal cortex on mood and behaviour in healthy volunteers by applying tDCS to the left and right frontal hemispheres.
The aim of the proposed research is to test the hypothesis that psychometric schizotypy (or psychosis-proneness, i.e. subclinical hallucinations and delusions in healthy people) is associated with reduced activation of brain circuits subserving self…
The objective will be to test the effectiveness of a web-based intervention aiming to reduce alcohol consumption and depression symptoms combined, a web-based self-help intervention focusing on problematic alcohol use only, and a waiting list…
The goal of this study is to test the effects of the VIPP-FC within a Randomized Controlled Trial (RCT). The expectations of this study will be fourfold:- Sensitivity of the parents and their sensitive disciplining towards the foster child will…
2.1 Primary The primary objective of the study is to evaluate the efficacy of troriluzole as adjunctive therapy compared to placebo in subjects with OCD who have had an inadequate response to their current OCD treatment based on the change in their…
This study aims to transdiagnostically evaluate effectiveness of guided Internet CBT for insomnia (ICBTI) to improve sleep, reduce emotional distress and improve responsiveness to regular treatment through sleep improvement, and to foster…
The aim of this research project is to assess the feasibility and acceptability of an adapted version of Group Interpersonal Therapy [IPT] for parents from refugee backgrounds in primary care in The Netherlands. Moreover, the potential effectiveness…
The study is designed to investigate why withdrawal of off-label antipsychotic drugs for behavioral problems in people with intellectual disability often fails by comparing two blinded groups (withdrawa group versus control group). This has led to…