67 results
The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…
1. the primary objective of this study is to examen the incidence and prevalence of PTSDand depression in pre-eclampsia patients after delivery2. a secondary objective is to identify risk factors during pregnancy, durante partu and postpartum…
(1) To determine the frequency of antibody-mediated encephalopathy in children with seizure-related or (sub)acute onset neuropsychiatric disorders. (2) To identify the target auto-antigens of selected seizure-related and (sub)acute onset…
Primary Objective: To investigate the behavioral effects of controlled discontinuation as well as the feasibility of discontinuing currently ongoing treatment with risperidone in children and adolescents with behavioral problems who have used…
Primary ObjectiveEstimate the proportion of subjects fulfilling criteria for symptomatic remission (as defined by Andreasen et al.)* following a transition to 12 months* treatment with flexible-dose PP3M in subjects with schizophrenia previously…
The aim of this (pilot) study is to investigate if stress affects memory and attention skills by impacting the dopamine and noradrenalinesystem.
To develop a 360o video VR relaxation program (VRelax) for reducing impact of stress in patients with depressive, anxiety and psychotic disorders. Feasibility, user-friendliness and immediate effects on subjective and objective stress reactivity…
Study I aims to explore dysregulation of biological stress systems among traumatized youths with and without ID in residential care, and compare them with a healthy control group. Study II aims to conduct a randomized controlled trial (RCT) to test…
The primary aim of this study is threefold. The first objective is to determine whether the SCL and the frequency of non-specific skin conductance response (nsSCRs) measured by the Philips GTEP Emography Bracelet are accurate measures of sympathetic…
The following research questions will be addressed in two different studies:1. Do addicted patients with high scores on psychopathy have reduced empathic concern associated with reduced LPP amplitude and mu-suppression during an empathy task? 2. Are…
To assess the effects of Cognitive Behavioral Therapy (CBT) in pregnant women with symptoms of anxiety or depression on the child*s behavioral/emotional problems. In addition, we aim to study its effects on the child*s development, maternal mental…
The primary objective is to investigate brain functioning during (reversal) fear conditioning and reward/punishment conditions during different experimental conditions. Secondary objectives include investigation of connectivity between brain…
The aim of this study is to investigate the feasibility and efficacy of a combined treatment for PTSD and problematic alcohol use (PAU) in a Dutch sample of older patients with PTSD and PAU. Expertise from Brijder addiction care will be shared with…
The aim of the present study is to investigate whether EMDR is an effective method to treat low self-esteem and if this is more effective than CBT. Hypothesis:1. Participants will improve on measures of self-esteem, psychological symptoms and social…
The proposed study has 2 main aims: 1) Understanding the complex interplay of determinants of parenting and examining how specific parenting styles explain associations between parent characteristics (such as personality or mental and physical (ill…
The objective of the proposed research is to address the effectiveness of neurofeedback and exercise as non-pharmacological treatments for ADHD. The effects of neurofeedback and exercise will be assessed on three domains: behaviour, neurocognition,…
The aim of this study is to investigate whether cognitive development, medical consultation patterns and genotype are predictive factors for the development of psychopathology in early adolescents and in what proportion they contribute.
Main: to examine the comparative and combined effects of aggression replacement training (ART) and Risperidone on aggressive behaviours among adolescents with aggression problems ages 14-21 across clinical and non clinical settingsSecondary: to…
To get insight into the prevalence of a whole range of psychiatric symptoms of parents of children who have been admitted to an outpatient clinic for child and adolescent psychiatry for various psychiatric symptoms and the parent-offspring…
The aim of study I is to compare the two working memory interventions, Cogmed and the intervention developed by the Bascule, in a sample of 100 children with ADHD and working memory deficits, aged between 8 and 12 years old. Effects on working…