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A placebo-controlled discontinuation trial of off-label used risperidone in people with intellectual disability

The primary objective of this study is: To study the effect of controlled discontinuation of long-term used risperidone, for the treatment of challenging behavior, on behaviour and health. Our hypothesis is that long-term use of risperidone for…

Off-label use of Risperidone in Children and Adolescents (ORCA): a double-blind placebo-controlled discontinuation trial

Primary Objective: To investigate the behavioral effects of controlled discontinuation as well as the feasibility of discontinuing currently ongoing treatment with risperidone in children and adolescents with behavioral problems who have used…

The role of catecholaminergic neurotransmission in attention and cognition

The aim of this (pilot) study is to investigate if stress affects memory and attention skills by impacting the dopamine and noradrenalinesystem.

ADHD Treatment at Home through E health? A Non-inferiority pilot trial and Examination of costs and consumer satisfaction of blended versus face to face parent training for children with ADHD and behavioral problems

The current pilot study will explore 1) whether the effect of blended parent training is noninferior to the effect of face to face parent training, 2) whether therapist time can be reduced by offering the intervention partially online, 3) whether…

First web-based Dual Disorder Treatment Trial among Problematic Alcohol Users with Moderate Depression Symptoms

The objective will be to test the effectiveness of a web-based intervention aiming to reduce alcohol consumption and depression symptoms combined, a web-based self-help intervention focusing on problematic alcohol use only, and a waiting list…

The PICAS-study: Validation of the Sexual Knowledge Picture Instrument (SKPI); about the verbal- and the nonverbal ways sexually abused children reveal sexual knowledge.

1) The validation of the SKPI used in children with a developmental age of 3 to 8 years old.Hypothesis:- By using the SKPI the examiner will be able to distinguish children who are victims of CSA from children who are not.2) The demonstration of the…

Diet and Aggression: Reducing aggression among chronic psychiatric inpatients through supplementation of multivitamins, minerals and n-3 fatty acids

The main objective in this study is to test the hypothesis that suppletion with vitamins, minerals and n-3 fatty acids in long-term psychiatric inpatients will reduce the number of aggressive incidents.

Elucidating the therapeutic mechanism of DBS by simultaneously stimulating and recording from the target brain region.

Our primary objectives are to decode **signatures** of activity from the electrode that might prelude or accompany an OCD attack, by analyzing its activity in an experimental setting and in real-life situations, and to correlate symptom changes with…