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Social gaze behavior during parent-child interaction: a dual-eye tracking study

This pilot study is aimed at assessing the feasibility and utility of a new dual-eye tracking setup. This method is designed to study gaze behavior during social interaction. This method has already been tested and validated with adults en now we…

Facial dysmorphologies associated with CNV expression in psychiatric illness

Primary objective: To evaluate whether intellectual disability and facial dysmorphology are associated with an increased clinical diagnostic yield of genetic testing among patients with a psychiatric illness.Secondary objective: To investigate the…

Early recognition of stress through biofeedback to decrease incidents in residential youth care

The main objective in this study is whether biofeedback on the psychofysiological stress level is effective in reducing incidents in youth in residential care.

The effectiveness of EMDR in young children (1,5 to 8 years) with PTSD

It is investigated whether EMDR is effective in reducing post-traumatic stress reactions in young children (1.5 to 8 years), reducing co-morbid emotional and behavioral problems and whether the results will be maintained 3 months after treatment. In…

An Open- Label, Phase 2, Multicenter Feasibility Study if Manualized MDMA-Assisted Psychotherapy with an fMRI sub-study Assessing Changes in Brain Activity in Subjects with Post-Traumatic Stress Disorder

The overall objective of this study is to use standard clinical measures to explore the safety and effects of open-label manualized MDMA-assisted psychotherapy with a flexible dose of MDMA in participants with severe PTSD, and to serve as an…

Pathogenic Antibodies and (Rapidly Progressive) Dementia syndromes

1) Establish a comprehensive clinical and antibody profile of autoimmune synaptic encephalitis in dementia syndromes. 2) To assess outcome and provide diagnostic guidelines who to test and in whom testing will be unnecessary, and elucidate…

A multicenter double blind randomized crossover study comparing the impact of dorsal versus ventral subthalamic nucleus deep brain stimulation on apathy in Parkinson*s disease

In this study, we will test whether STN-DBS related apathy can be reversed by switching stimulation to a more dorsal contact on the electrode.

The resilient brain of preterm born children

The primary objective is twofold. First, we aim to investigate how the brain responds to acute stress and, second, which factors explain variability underlying brain activity following acute stress. The study population consists of extremely preterm…

Virtual Reality aggression prevention training for people with mild intellectual disabilities (VRAPT-ID)

Primary Objective: The objectives of this study are to adapt the VRAPT protocol and manuals for people with MBID, and to test the feasibility of VRAPT-ID in a sample of people with MBID and aggressive behavior. Feasibility will be assessed by…

Integration of medical, psychiatric and behavioural care for the substantiated and appropriate use of psychotropic drugs in individuals with an intellectual disability and challenging behaviour.

The main objective of this study is:This study investigates whether diagnosis and treatment of challenging behaviour, as provided by an specialist team of mental health care professionals and intellectual disability professionals, when optimising…