34 results
Our primary objective is to investigate whether oxytocin administration can affect empathy and emotion recognition in healthy and antisocial adolescents. We expect that oxytocin will enhance empathy and emotion recognition in both healthy and…
The present study focusses especially on the value of cognitive skill training within a program of work integration by means of IPS. Research shows that these interventions indeed lead to enhanced cognitive skills (Wykes et al. 2011). According to…
The primary goal of the study is to evaluate the effect of CAT on daily functioning and community participation, and thereby psychosocial well-being. Secundairy goals are evaluating the implementation of CAT in the usual care and eveluation of the (…
Primary objective- To assess the effects of Org 25935 on heavy drinking in subjects with alcohol dependence.Secondary objectives- assess the effects of Org 25935 on the amount of drinking- To assess the effects of Org 25935 on the first relapse to…
To establish if and how the endocannabinoid system is involved in ADHD and related symptoms. This will be investigated by assessing the acute effects of a cannabinoid agonist (THC) on brain function related to ADHD and ADHD symptoms.
The proposed research project will examine the potential benefits of a *gamified* working memory training for adolescents in addiction care. The primary objective is to test whether a gamified working memory training will lead to improved working…
We want to study the effect of feedback to the clinician concerning the motivation of the patient to see if this feedback leads to a better motivation, compliance and treatment result because the clinician is more aware of the motivation (or the…
The main objective of this study is to determine whether THC, the primary psychoactive ingredient in cannabis, modulates activity in functional brain systems. We test this by assessing the acute effects of THC on the reward system, the working…
The main objective of this study is to determine whether and how the endocannabinoid system is involved in psychiatric disorders. We test this by assessing the acute effects of a cannabinoid agonist (THC) on brain systems that are known to be…
In this study, two forms of feedback and one control condition are compared:* Control group: the therapist gets no feedback.* Outcome monitoring feedback: the therapist gets feedback on the patients progress in a progress chart.* Complex feedback…
Primary:* To investigate the safety and tolerability of the co-administration of GSK598809 at175 mg and ethanol in healthy volunteers.* To examine the potential pharmacokinetic interactions between GSK598809administered at 175mg and ethanol in…
• Identify regional specificity of dopaminergic drug effects, i.e. the distinct behavioural roles of dopamine in the striatum and dopamine in the prefrontal cortex.• Identify receptor specificity of dopaminergic drug effects, i.e. the distinct…
The main objective of the study is to find an instrument that can be used to objectively establish improvement in adults with ADHD with treatment with OROS-Mph, so that adherence to treatment can be increased and so that patients and docters can…
The objective of this pilot is to establish if CVS has any effect on patients with this psychogenic disorder in self-related cognition after psychotrauma and forced migration, and if so, to describe this effect in comparison with the effect CVS has…
To assess whether treatment with DBS can reduce or resolve TDD and if DBS can induce beneficial or side effects in particular psychiatric and or cognitive symptoms.
Primary objective: Investigate the effects of a stress task on resting state and task-induced functional connectivity in patients with bipolar I disorder. Secondary objective: - Correlate the endocrine response to mental challenge to resting state…
The first goal is to test whether the temporary disruption of the right TPJ leads to changes in the functional connectivity between brain areas that are related to body awareness.Second, the study intends to test how temporary inhibition of the TPJ…
To characterise and compare neurobiological mechanisms underlying behavioural effects of three different rTMS treatment protocols in OCD using multimodal neuroimaging, with a focus on neuroplasticity.
To investigate whether VR-VOICES is more effective than regular treatment for voicehearing in patients with auditory hallucinations.
The main objective of this study is to investigate whether rTMS treatment will improve clinical outcomes in body dysmorphic disorder, by reducing BDD YBOCS outcomes. Furthermore to improve localization and rTMS treatment in the dorsolateral…