26 results
The aim of this project is to test the hypothesis that MDD patients with disturbances in anger/aggression regulation have more serotonin disturbances, as a trait marker for relapse, than MDD patients without disturbances in anger/aggression…
Primary Objective: * To determine the effects of pharmacogenetic screening for CYP2D6 on the time to reach adequate serum drug levels according to the guidelines.Secondary Objective(s): * To determine the effects of pharmacogenetic screening for…
To compare cerebral activity patterns during emotional and cognitive processing among depressed patients with CKD and patients with regular depression.
This study aims at the questions about anterograde amnesia. How often does it occur in patients being treated with bilateral ECT for a depressive disorder, how does anterograde amnesia develop during the treatment course and how does it subside…
1. We will explore the feasibility of homeopathic treatment with a semi standardised homeopathic prognostic treatment protocol for PMS in daily homeopathic practice. 2. We will evaluate the prognostic validity of using a semi standardised prognostic…
Phase I: To investigate whether it is feasible to organize an international multi-centre pragmatic trial on individualised homeopathic add-on treatment using a semi-standardised algorithm in women with premenstrual disorders and usual care only. We…
Objectives: - To identify and compare motivational behaviour in patients during different phases of cancer treatment. - To test its associations with self-reported fatigue/depression. - To determine to what extent treatment regimen, inflammation,…
To assess utility and accuracy of an electroencephalography (EEG) -based brain network analysis platform as potential diagnostic tool for MDD, to correlate digital biomarkers and *gold standard* psychometric questionnaires such as MADRS in MDD and…
We aim to illustrate the relationship between early-life-adversity and emotional memory performance, and whether schema related neural activity during encoding and retrieval will contribute to the negative memory biases.
Primary:o To compare effort- and/or reward-related neural activity between cancer survivors and healthy controlso To assess whether cancer-related fatigue is related to effort- and/or reward-related neural activitySecondary objectives:o To assess…
The primary aims are to test the hypothesis that in depressed patients, an mPFC-related presence of negatively toned memory schemas contributes to a preferential encoding and subsequent REM sleep-related consolidation of negative stimuli, thus…
We investigate: (1) whether young women can be grouped according to distinct trajectories of depressive symptom change, measured with the Major Depression Inventory (MDI), over a period of 8 months following the breakup of a romantic relationship; (…
The number of psychiatric patients who received euthanasia has grown from 0 in 2002 to 83 in 2016. Also the estimated number of requests has risen, from 320 in 1995 to 1100 in 2016. Although the numbers are relatively low and most of the requests…
Our primary objectives are to study: 1) differences in the brain*s sensitivity to the effects of light on emotional processing in people with PD and people with depressive symptoms compared with healthy controls 2) whether different spectrum of…
Primary Objectives* To characterize patients with unipolar depression in terms of social, physical, biometric activity, and neurophysiological and -psychological data outcomes using digital technologies * Evaluating the feasibility and subjective…
The aim of this study is to compare directly the activity of dopamine (DA) and norepinephrine (NE) in humans when they perform tasks that measure different aspect of cost-benefit evaluation (decision-making and learning) It is expected that blockade…
Primary Objective: To assess whether CYP450 genotype guided dosing of TCAs results in faster attainment of therapeutic plasma concentrations compared to dosing as usual. . Secondary Objectives: * To assess whether genotype guided dosing results in…
To investigate the impact of the multispecies probiotic product Ecologic*Barrier on neurocognitive measures of emotion and executive functioning.
The primary objectives are (1) to investigate the feasibility of online courses targeting nutrition and food-related behaviour and (2) to investigate whether the feasibility of the online courses is related to depressive symptoms. The secondary…
Aim of the study is to evaluate the effectiveness and cost-effectiveness of a positivity training based on attention bias modification as waitlist-intervention for adult outpatients with a major depressive disorder.