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EMG registration of the pelvic floor and pelvic floor muscle activity patterns during, abdominal, hip adductor, and gluteal muscle contractions in healthy women

To describe the EMG activity of the pelvic floor muscles (PFM) with a bi-polar EMG probe and the MAPLe and effect on the registered EMG activity with the probes in relation to the contractions of the muscles surrounding the pelvic floor. To describe…

Natural course, effects of enzyme therapy and health economic aspects in patients with mucopolysaccharidosis type I, II and VI. Long-term folloe-up of untreated patients and patients receiving commercially available Aldurazyme, Elaprase and Naglazyme.

the objective of the current study is to evaluate the safety and efficacy of enzyme therapy in the Dutch population of patients with MPS I, II and VI; to compare this to the natural course of these diseases; to make an inventory of the direct and…

Viscosity of PMMA Bone Cement in Percutaneous Vertebroplasty for Osteoporotic Vertebral Compression Fractures: A Randomized Controlled Trial

Establishment whether usage of high viscosity PMMA bone cement in PVP for OVCFs leads to a reduction in leakage incidence compared to usage of conventional (low-medium) viscosity PMMA bone cement in PVP for OVCFs.Since evidence is scarce or…

Inter- and Intraobserver Variability of Determination of the Elbow Center of Rotation.

To compare surgeon assessments of the elbow COR with the digitally measured COR, and to determine the accessory inter- and intraobserver variability.

Prevalence of Psoriatic Arthritis in Adults with Psoriasis: An Estimate From Dermatology Practice

The purpose of this study is to determine whether psoriatic arthritis (PsA) can be detected in an early stage by the dermatologist, with the diagnosis of the rheumatologist as a "gold standard" for presence of this disorder. Futhermore it…

Rotator Cuff Calcific Tendonitis: Needle UltraSound-guided treatment vs. Subacromial corticosteroids: a randomized controlled trial

To compare short (6 weeks, 3 months) and longer term (6 months, 1 year) results of ultrasound-guided barbotage treatment combined with subacromial corticosteroid injection treatment, versus ultrasound-guided treatment with subacromial…

Prospective randomized study of the effect of autologous concentrated thrombocytes versus corticosteroid injections in lateral epicondylitis.

The objective of this study is to prove that a single injection of PRP in the COE decreases the pain and duration of the condition in patients with chronic lateral epicondylitis compared to injection with lidocaine and corticosteroids.The specific…

Top Institute Pharma (TIP) - research UMCU-rheumatology:
*Metabolic adverse events/co-morbidity in chronic rheumatoid arthritis patients*

- To systematically determine the influence of disease activity of RA on the metabolic syndrome of patients with chronic RA (disease duration > 2 years).

Prospective randomized study of the effect of autologous concentrated thrombocytes versus corticosteroidinjection in lateral epicondylitis.

The objective of this study is to prove that a single injection of PRP in the CEO decreases pain and duration of the condition in patients with chronic lateral epicondylitis compared to injection with lidocaine and corticosteroids.The specific…

Interbody fusion devices in the treatment of cervicobrachial syndrome; a blinded randomised trial of cancellous structured ceramic (CSC) versus PEEK cages.

To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.

A Stratification trial to determine key immunological factors predicting Tofacitinib efficacy in Psoriatic Arthritis (PsA). TOFA-PREDICT

This study has been transitioned to CTIS with ID 2024-510903-12-00 check the CTIS register for the current data. Primary objective:Identify pre-treatment profiles with integrated clinical, transcriptomic, metabolomic, proteomic, flow cytometric, and…