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Treatment of osteoporosis with unfocused extracorporeal shock wave therapy: pilot study

A clinical pilot-study were we will look if one time shock wave therapy on the distal radius leads to an increased bone mass. At the same time we would like to study if shock wave therapy of the distal radius could result in complications and we…

A multi-centre randomised double blind, placebo and active controlled parallel group study to investigate efficacy and safety of ONO-5334 in post menopausal women with osteopenia or osteoporosis.

The objective of this study is to investigate if use of ONO-5334 has a more positive effect on bone density and biochemical markers of bone turnover than Alendronate (a bisphosphonate) and placebo.

A proof-of-concept study of SB-751689 in male and female with a fractured distal radius.

To evaluate the effects of SB-751689 on the time to radiographic healing, defined as the interval in days between the occurrence of the radial fracture and the time of complete bridging and/or disappearance of fracture line at 3 of the following 4…

A clinical, prospective feasibility study to assess the effectiveness and safety of micro-structured TCP granules as a bone augmentation material in sinus floor elevation procedures.

The primary objective is to determine whether micro-structured TCP granules provides sufficient bone volume as basis to insert endosseous dental implants in a two staged sinus floor elevation technique by benefiting from the clinical handling…

Stereotactic body radiotherapy followed by surgical stabilization for patients with painful unstable spinal metastases: First-in-man study according to the IDEAL recommendations

Primary Objective To assess the feasibility and safety of combining stereotactic body radiotherapy and pedicle screw fixation in a 48-hour window for the treatment of painful unstable metastases of the thoracic and/or lumbar spine.Secondary…

A Randomized, Blinded, Placebo-controlled, Phase 2 Study of INBRX-109 in Unresectable or Metastatic Conventional Chondrosarcoma

This study has been transitioned to CTIS with ID 2024-517528-20-00 check the CTIS register for the current data. Primary objective:• To evaluate the anticancer efficacy of INBRX-109 in the intention-to-treat (ITT) population as measured by…