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Unilateral condylar mandibular fracture: anatomical position, functionality and quality of life.
Is anatomical reduction of conservatively treated unilateral condylar mandibular fracture related to functional and to subjective outcome?

The aim of this study is to describe whether anatomical reduction in closed treated unilateral condylar mandibular fracture and objectively measured masticatory performance are related.

Unilateral condylar mandibular fractures: Conservative treatment vs. open reduction and internal fixation. A multi-centre prospective study

Is there a significant difference in functional outcome of the three treatment modalities for unilateral condylar mandibular fractures?

Cast-OFF trial: One versus four-five weeks cast immobilization for non reduced distal radius fractures. A randomized clinical trial. A feasibility study.

The aim of this feasibility study is to define whether one week of plaster cast treatment is possible and can lead to better functional results, with at least the same patient satisfaction and complications. This feasibility study will be used to…

Prediction of non-union in diaphyseal fractures

Based on the risk-factors a prediction model for non-union will be developed. Also the effect of a initial vitamin D deficiency on fracture healing will be investigated.

Accuracy of diagnostic imaging techniques in patients with a suspected fracture-related infection

The primary aim of our *Imaging of Fracture-related Infections trial (IFI trial)* is to assess the diagnostic accuracy of all commonly requested medical imaging techniques (WBC scintigraphy, FDG-PET/CT and MRI). The secondary aim is to establish…

Nonoperative treatment of dorsally dislocated distal radius fractures in adults with an individualized 3D printed brace; a tolerability study in healthy volunteers and patients

Part 1 aims to determine the tolerability of the 3D-printed brace when worn by healthy volunteers (50 years of order), performing their normal daily activities. In part 2, the objective is to determine tolerability of the 3D-printed brace in…

Analysis of instability patterns in acute scaphoid fractures by 4-dimensional computed tomographic imaging

Despite the severe clinical consequences of a scaphoid nonunion, the kinematical mechanisms that influence the healing process of a scaphoid fracture are still poorly understood. Until now, all in-vivo research is based on step-wise static imaging…

Clinical outcomes of coracoid fractures

Currently there is little scientific data about the clinical outcomes of the conservative and operative treatment of coracoid fractures. Most of the studies performed are case reports or retrospective studies with a small population. Therefore, we…

Disentangling the cause of atypical femur fractures associated with the use of bisphosphonates

Primary Objective: to identify risk factors and the underlying mechanism of AFFs by:- setting up a database with detailed information to define patients* characteristics.- building a biobank with urine and blood samples from these patients. -…

Diagnostics and fracture healing of scaphoid fractures with High-Resolution Peripheral Quantitative Computed Tomography (HR-pQCT)

Phase I - Diagnostic phaseThe primary objective is to compare the clinical diagnostic performance of HR-pQCT with conventional CT imaging for diagnosis of scaphoid fractures.We hypothize that the use of the HR-pQCT in patients with a suspected…

Negative pressure wound therapy for surgical wounds of the foot and ankle

Primary Objective: The primary objective of this study tTo determine the feasibility ofreduce the amount of surgical site infections using prophylactic NPWT in patients undergoing surgery to the foot and/or ankle. The NPWT device which we will use…

Analysis of the kinematical pattern in scaphoid nonunion by 4-dimensional computed tomographic imaging

This will be the first study to investigate dynamic wrist motions patterns, by a novel 4D-CT method, in patients with scaphoid nonunion and will give us dynamic information of the carpal bones before and after surgery. We will specifically test the…

eraSmus medIcal ceNTer skEletal fRagility study

The aim of this study is to evaluate the added benefit of integrating genetic information and state-of-the-art phenotypic information (clinical measurements) of the musculoskeletal system in groups of patients with conditions presenting with or at…

A prospective, single-cohort, multicentre clinical investigation to evaluate the performance of
POROUS R3C ultrasound device for fracture risk prediction in middle-aged and elderly men
and women

Primary objectivesPart 1:• To establish a corrected standardized gradient of fracture risk using the POROUS R3C ultrasound device based on prevalent fractures.Part 2:• To establish a corrected standardized gradient of fracture risk using the POROUS…

The development of a prediction model for acute pain transitioning into pain persisting for more than 3 months after a visit to the emergency department

We hypothesize (based on literature) that the incidence of chronic pain in The Netherlands is around 15-20% in patients presenting to the emergency department with (acute) pain related complaints. We have no further hypothesis, because of the…