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Game Ready continuous-flow cryo- and cyclic compression therapy after fracture treament of the hip: a prospective multicenter, open-label, multicenter, randomized, controlled, clinical trial on postoperative effects on pain.

The goal of the study is whether to establish if application of combined cyrocompression therapy directly postoperative after hip fracture surgery results in a significant reduction in painperception en whether this reduces the morfine consumption.…

Antibiotic prophylaxis and prevention of wound infections following implant removal after foot, ankle and lower leg fractures

In light of the above, our objective is to study the (cost-) effectiveness of a single intravenous gift of antibiotic prophylaxis with a firstgeneration cephalosporin prior to implant removal following surgical fixation of foot, ankle and/or lower…

Application of the game ZELFIE for elderly at home, in order to live longer independently

The aim of the present study is to implement and evaluate the 'ZELFIE game' in vulnerable geriatric patients after hip-surgery, and in patients with an increased risk of falling. The game is specifically tailored to and co-created with the…

Effects of fall training on fall severity in healthy elderly subjects

The purpose of this pilot study is to evaluate the fall training in older individuals by reduction of hip impact forces. Furthermore, to determine if older individuals are able to perform these fall techniques after training, fall performance is…

The risk of pressure soars after use of pelvic circumferential devices

The aim of this study: - To determine the amount of pressure of PCCDs on the skin. The Pelvic Binder, SAM Sling and T-POD will be compared.- To determine the influence of body mass index on the pressure characteristics of these 3 types of PCCDs.The…

Anticoagulant treatment after knee arthroscopy or during plaster cast lower leg immobilisation: determining the balance between benefits and risks

Comparative effectiveness research to determine cost-effectiveness of an existing healthcare policy, i.e. treatment with low molecular weight heparin (LMWH) after knee arthroscopy and lower leg plaster cast immobilization following surgical or…

Cast OFF-2: One versus four-five weeks of plaster cast immobilization for non-reduced distal radius fractures. A randomized stepped wedge design.

It is our hypothesis that one week of plaster cast treatment will give a better functional outcome score as Patient Rated Wrist Evaluation (PRWE) and a lower pain score at 6 weeks post injury and will be less costly as compared to the control group…

Operative treatment of AO Weber B fibular fractures with additional posterior malleolar fragment: reduction and functional outcome after prolonged follow up

To asses if there is a difference in functional outcome between open reduction and fixation of the posterior fragment in trimalleolar AO-Weber B fractures with additional medium-sized posterior fragment (5-25% of the involved articular surface, AO…

Wound Infections following Implant Removal below the level of the knee; the influence of 2g of prophylactic Cefazolin

The primary objective is to study the effectiveness of a single intravenous dose of 2g of cefazolin on SSIs after IR following fixation of foot, ankle and/or lower leg fractures. Secondary objectives are to study the cost-effectiveness of 2g of…

Delirium in Elderly Patients with Trauma of the Hip

The DEPTHip Study aims to shed light on the question whether the use of a continuous ultrasound-guided FICB employing catheter technique, administered in the ED within 2 hours after presentation of an elderly patient with a hip fracture, can…

The (cost-)effectiveness of dynamic bracing versus standard care alone in patients suffering from osteoporotic vertebral compression fractures

1. Effect evaluationTo assess the effectiveness of dynamic bracing on quality of life in patients suffering from an osteoporotic vertebral compression fracture (OVCF).2. Economic evaluationTo examine whether dynamic bracing compared to standard care…

TArget-Site Concentrations of prophylactic cefazolin in foot and Ankle surgery

To analyze the difference in fT>MIC at the target site and infection rate for a single dose of 1 and 2g of cefazolin.

Cast-OFF trial: One versus four-five weeks cast immobilization for non reduced distal radius fractures. A randomized clinical trial. A feasibility study.

The aim of this feasibility study is to define whether one week of plaster cast treatment is possible and can lead to better functional results, with at least the same patient satisfaction and complications. This feasibility study will be used to…

Negative pressure wound therapy for surgical wounds of the foot and ankle

Primary Objective: The primary objective of this study tTo determine the feasibility ofreduce the amount of surgical site infections using prophylactic NPWT in patients undergoing surgery to the foot and/or ankle. The NPWT device which we will use…

The development of a prediction model for acute pain transitioning into pain persisting for more than 3 months after a visit to the emergency department

We hypothesize (based on literature) that the incidence of chronic pain in The Netherlands is around 15-20% in patients presenting to the emergency department with (acute) pain related complaints. We have no further hypothesis, because of the…