116 results
- To investigate different pathogenetic mechanisms underlying the clinical syndrome termed RA - To investigate changes in the synovial tissue in relationship to the duration of disease- To identify new therapeutic targets in the synovial tissue in…
The primary objective is the assessment and comparison of the in vivo kinematic patterns of the knee designs by means of fluoroscopy and EMG. The secondary objective is to evaluate if the polyethylene bearing in the mobile bearing is rotating and if…
The objectives of this study are answering these two questions:1. Do patients with KR-R show a clear and fast recovery of walking?2. Are there any other parameters that improve clearly and quickly after KR-R?
Primary objective: Evaluate changes in cartilage glycosaminoglycan content using dGEMRIC, in patients with osteoarthritis of the knee undergoing axial correction (HTO, femur osteotomy)Secondary objective: Correlate quantitative MRI data to…
The goal of this study is to perform a kinematic evaluation of the Duracon knee prosthesis (Stryker, USA), by means of fluoroscopy and EMG. The findings of this study will contribute to improve total knee designs and improve rehabilitation…
The influence of activity level right before the MRI is made is unknown. I seems clear that more activity results in more hydrops and so results in a larger pseudotumor. The objective of this study is to investigate the possible influence of timing…
Objective main studyObjectives to develop diagnostic and imaging tools to identify early RA-patients and stratify established RA-patients for individualized treatment strategies.Objective ultrasound study (amendment)-To compare inflammatory…
Assessment of value of DECT scan in diagnosing acute arthritis, caused by gout
In the specified patient groups, quantitative outcomes will be compared in both weight-bearing images and non-weight-bearing images. In detail, the location, displacement and rotation of individual bone fragments in the foot will be measured in 6…
The primary objective is to quantify the degree of shoulder instability by determining the contact surface area between the glenoid and the humerus together with the translation of the humeral head during motion using three-dimensional CT scanning.…
The main objective is to assess whether transcatheter arterial embolization of neovessels in patients with symptomatic knee OA results in significant pain reduction after 4 months compared to sham treatment.We hypothesize that novel transcatheter…
The aim of the four imaging studies in this combined protocol is to investigate the bilateral symmetry of the human ankle joint using quantitative 3D computed tomography (Q3DCT); the accuracy of the medial distal tibial angle as measured on two…
pSS: • To compare the efficacy of branebrutinib with PBO at Week 24 in the treatment of subjects with pSS• To compare the safety and tolerability of branebrutinib with PBO in subjects with pSSRA: • To compare the efficacy of branebrutinib with PBO…
The goal of this study is to measure the amount of movement of the knee prosthesis in relation to the bone with the use of the Comforthod system. So an objective discrimination can be made whether a prosthesis is loose or fixed.
The aim is to investigate the therapeutic effects of Secukinumab on bone formation in SpA patients by using [18F]Fluoride PET-CT imaging, and to investigate cellular and molecular pathology in bone formation.
1. To unravel which factors (altered CPP, structural, functional, metabolic, inflammatory and psychological factors measured presurgical) are predictive for an unsatisfactory outcome 1 year after a primary TKR (longitudinal).2. To unravel the…
To validate the findings on the diagnostic value of hand and foot MRI for early detection of RA in an independent sample set.
Objective: We aim to 1) monitor and investigate the change in serum metal ion (Cobalt and Chrome) levels postoperatively (at 3-6, 12 and 24 months) in patients receiving a primary PEEK HD coupling mechanism, monitor and investigate the change in…
The objective of this study is to demonstrate that arthroscopic synovectomy of the wrist comined with deposition of intra-articular corticosteroids (DIACS) will lead to better functional outcomes compared to intra-articular corticosteroid injection…
This study has been transitioned to CTIS with ID 2024-510903-12-00 check the CTIS register for the current data. Primary objective:Identify pre-treatment profiles with integrated clinical, transcriptomic, metabolomic, proteomic, flow cytometric, and…