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Assessment of intraoperative embolism during spinal surgery with transesophageal echocardiography.

Our primary study objective is whether visualizing and scoring of emboli is technically feasible. Secondary we want to asses the occurence and incidence of embolic events during spinal instrumentation surgery by intraoperative monitoring with TEE.…

prospective follow-up of focal Bone Mineral Density changes in the inter-transverse fusion mass after instrumented single-level posterolateral lumbar spine fusion

The purpose of our study is to evaluate modern dual-energy x-ray absorptiometry scan techniques (iDEXA; General Electronics, USA) as an adjunctive diagnostic tool to evaluate the ongoing process of spinal fusion. Changes in bone mineral density (BMD…

Top Institute Pharma (TIP) - research UMCU-rheumatology:
*Metabolic adverse events/co-morbidity in chronic rheumatoid arthritis patients*

- To systematically determine the influence of disease activity of RA on the metabolic syndrome of patients with chronic RA (disease duration > 2 years).

Prospective randomized study of the effect of autologous concentrated thrombocytes versus corticosteroidinjection in lateral epicondylitis.

The objective of this study is to prove that a single injection of PRP in the CEO decreases pain and duration of the condition in patients with chronic lateral epicondylitis compared to injection with lidocaine and corticosteroids.The specific…

Interbody fusion devices in the treatment of cervicobrachial syndrome; a blinded randomised trial of cancellous structured ceramic (CSC) versus PEEK cages.

To compare functional recovery of the patient and the fusion status of ceramic cages versus PEEK cages on the short and long term.

Imaging Inflammation of the Cervical Dorsal Root Ganglion before and after Anterior Cervical Discectomy: a Pilot study

In the literature the effectiveness of the anterior cervical discectomy is measured using subjective validated questionnaires.It would be an important improvement if it is possible to detect the inflammatory process of the dorsal root ganglion with…

Assesment of the stiffness of the trunk by the Scolibed

Determine the repeatability, inter and intra-observer variability of the *Scolibed*. Determine the variation in stiffness for healthy individuals and for scoliotic patients. Compare the results of healthy individuals and scoliotic patients.

Effect of Lumbodorsal Skin Displacement on Lumbopelvic Range of Motion, Flexion-Relaxation Ratio, and Skin-Fascial Shear-Strain Ratio in nonspecific Low Back Pain patients.

With this research, we are examining the impact of skin displacement in individuals with chronic low back pain. We are investigating its effects on the mobility of the back and hip, as well as its influence on muscle activity in the back and…

Central sensitisation in patients with chronic low back pain radiating to the leg

To determine the presence or absence of central sensitisation in patients with CLBPr and to determine the effect of segmental nerve interventions on central sensitisation.

Hyperkyphosis and the Cobb angle: is the Cobb angle affected by posture in older adults?

To investigate: (1) the difference in degrees between a Cobb angle measured in supine position and standing position with standard instructions of the radiographer (main objective)(2) the correlation between the Cobb angle in both supine position…

Aspects of bracing in adolescent idiopathic scoliosis

Objective: The primary objective of the study is determining the contributing factors in  bracing for AIS. The contributing factors are determined as factors of influence in the  corrective possibilities and therefore end term…