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A Study of Respiratory Muscle Strength, including Effort-Independent Measures, in Subjects with Late-Onset Pompe Disease

The primary objective of this study is to compare respiratory muscle strength values obtained using volitional techniques with values obtained using non-volitional techniques. The secondary objective is to compare the change for these two sets of…

A randomized, two-arm, prospective, subject blind study to assess the safety and efficacy of InSpace* device in comparison to full thickness massive rotator cuff repair in subjects scheduled for a repair surgery.

This is a post-marketing study to further assess the safety and efficacy of the InSpace* device implantation in comparison to surgical repair of full thickness MRCT . The efficacy will be assessed by comparing the pre- and post- operative shoulder…

Vitamin D suppletion and aspecific musculo-skeletal disorders

To investigate the effect of suppletion of vitamin D on aspecific musculo-skeletal disorders

An Open-Label Extension Study of Patients with Late-Onset Pompe Disease Who Were Previously Enrolled in Protocol AGLU02704

The objective of this extension study is to assess the long-term safety and efficacy of Myozyme treatment in patients with Late-Onset Pompe Disease who were previously treated under the placebo-controlled, double-blind study AGLU02704.

Treatment of Myogenic Cranio Mandibular Dysfunction (CMD):
a prospective randomised clinical trial, comparing a mechanical stretching device (TheraBite®) with standard physiotherapy

To evaluate if a mechanical stretch device is effective in treating myogenic disturbances of the jaw joints, as compared with fysiotherapy.