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Longitudinal Aging Study Amsterdam, a solid infrastructure for the social science of ageing in the oldest-old

The aim of the study is to expand an existing infrastructure for scientific research, i.e. a longitudinal observational study, for investigating physical, emotional, cognitive and social trajectories of functioning, their determinants and their…

An explorative prospective observational case-control pilot of EEG registration of cortical spreading depression in patients aged 4 years or older, with an acute migraine attack admitted at the headache outpatient service of Medisch Spectrum Twente

Primary Objective: To measure cortical spreading depression with full-band EEG during the migraine attack at patients aged 4 years or older. Secondary Objective(s): -To explore (additional) signal analysis techniques for detecting CSDs or infra slow…

The effect of acute exercise and fitness level on the aging brain, an investigation with fMRI

The main objective of the study is to investigate (1) whether acute exercise influences brain responses to a working memory task, (2) the effect of acute exercise on CBF responses to acute aerobic exercise and (3) whether fitness level is related to…

Social Network Analysis of Risk behavior in Early adolescence (SNARE) Genetics

The main objective of this study is to collect DNA within the frame of an existent study to bring together detailed, longitudinal data about adolescents* risk behaviors and peer relationship networks with information on genetic markers. Proposed…

The ironHand system integrates both support in ADL and functional training exercises to improve impaired hand function

The primary objective of the present study is to examine the orthotic and therapeutic effect of the ironHand (iH) system, consisting of both an assistive and therapeutic module, by elderly and diagnosed patients with hand function problems, after…

Examining the longitudinal associations between negative peer experiences on adolescent inflammation

The main objective of this study is twofold: 1) To investigate the additive and interactive effects between negative peer experiences at the group level (i.e., peer victimization, peer rejection) and at the dyadic level (e.g., friendship) on…

Effectiveness of an online cognitive behavioral group intervention for adolescents with a chronic disease and parents: A randomized multicenter controlled trial

The main objective of the study is to research the effectiveness of two online cognitive behavioural therapeutic courses; a course for adolescents with a chronic illness and a course for parents of children and adolescents with a chronic illness.…

Anesthesia Geriatric Evaluation on predicting health related quality of life after peripheral vascular surgery in elderly patients.

1. To determine the influence of frailty on predicting an increase in HRQL in elderly peripheral vascular surgery patients. 2. To develop an 'AGE-VASC score' for predicting an increase in HRQL after cardiac surgery based on surgical risk…