91 results
The main objective of this study is to assess the acute effect of co-ingested vinegar on postprandial plasma glucose levels in type 2 diabetes patients.
Do high plasma free fatty acids lower central serotonergic responsivity?
However, prior to further implementation of this programme, insight into the effectiveness is needed.Specifically, what is the effectiveness of a targeted prevention programme with regard to the prevention of DM and *in the long-term- DM-related…
The purpose of the study is to confirm the skin test results in patients based on results of the control population of healthy volunteers never exposed to taspoglutide or any product with a similar mechanism of action.
The main objective is to elucidate the acute effects of an oral intake of either saturated, monounsaturated or polyunsaturated fatty acids on PBMC whole genome expression of obese and type 2 diabetic obese subjects. Secondary objectives are to…
Objective of the study:1) To assess insulin sensitivity and response in critically ill septic neonates and children.2) To determine protein balance in septic, critically ill children at baseline and during a HyperinsulinemicEuglycemic Clamp, while…
The goal of this study is examining the acute effects of insulin on microcirculation in hypertensive insulinresistant subjects and investigate if angiotensine II influences these effects. Amendement: The goal of the amendement is to exame the…
The objectives of the present study are twofold:1 screening patients with diabetes type 2 for psychological risk factors and2 studying the effect of a self-management training on metabolic regulation in patients starting with insuline therapy
The aim of this study is to test the hypothesis that obesity and the microbial community in the human GI tract are linked
1. To evaluate whether patients with FCH have different pattern of hypothalamic neural activity compared to healthy control subjects, 2. To evaluate whether patients with FCH (index patients) have a different pattern of hypothalamic neural activity…
The present study examines an extended version of this intervention that aims to address more challenging self-management goals once patients have mastered the skills necessary to achieve relatively small improvements in their self-management. The…
Does bilateral deep brain stimulation of the subthalamic nucleus in patients with Parkinson's disease influence plasma triglycerides and glucose metabolism?
The primary study objective is to investigate the contribution of peri-operative suppletion of bile to the preservation of bodyweight (expressed in kilograms).Secondary study objectives:1.To determine the contribution of peri-operative suppletion of…
The major research question is:Does a low-GI food product improve in healthy and obese men postprandial plasma concentrations of inflammatory markers as compared to a high-GI product?Major null hypothesis, H0:In healthy as well as obese men, a low-…
1. The primary aim of the study is to investigate whether periodontal treatment results in a decrease of plasma biomarkers that are related to cardiovascular diseases (CVD) and metabolic syndrome (MS) and what is the effect of the treatment on the…
The first objective of this study is to develop a screening program for the Hindustani Surinamese population and to test its feasibility. The second objective is to develop a lifestyle intervention aimed at preventing DM, targeted to the Hindustani…
To what extent does the use of therapeutic footwear, which is prescribed and monitored using plantar pressure distribution assessment, result in a reduced plantar ulcer recurrence rate compared to the use of therapeutic footwear which is prescribed…
Fracture healing groupPrimary outcome: to study the healing of distal radius fractures in terms of calculated bone strength based on the results of cortical and trabecular bone parameters using a novel HRpQCT technique (XtremeCT device, Scanco,…
The main objective is to compare the effect of immediate (or pre-existent) administration of daily calcium supplementation (1 Cacit bruisgranulaat *1000*: 1000 mg calcium) or two daily dosages of calcium + vitamin D (CaD® sachet 1000/880: 1000 mg…
The objective of the study is to investigate the glucose lowering potential and safety of continuation of Metformin during non-cardiac surgery, compared to discontinuation of Metformin 24 hours before surgery.