53 results
Primary Objective: We aim to create a prediction model to predict islet graft function at 3 months post-transplantation, using early islet graft function assessed in the first week after islet transplantation.Secondary Objective(s): - To determine…
The purpose of this study is the evaluation of InPen* with InPen* 2.0 app and Guardian* 4 system in adult patients with type 1 diabetes for the design of a future study.
This study aims to determine the effect of nocturnal versus daytime cyclic infusion of parenteral nutrition in adult chronic intestinal failure patients on bone turnover, glucose metabolism, nitrogen balance, sleep and wake rhythm and clock genes…
Primary objectives: - To examine how environmental exposures influence the prevalence, 5-year incidence and progression of cardiometabolic and chronic respiratory disease in the general population. - To determine the mediation effect of lifestyle…
To determine the effects of tissue-specific (adipose tissue or muscle) vs global (combined) IR on hepatic triglyceride biosynthesis in humans. To determine differential effects of an acute exercise intervention on hepatic triglyceride biosynthesis…
We aim to investigate the efficacy of a novel eating disorder prevention program, the Diabetes Body Project, specifically targeting young females T1D. Firstly, we will test the hypothesis that Diabetes Body Project will produce significantly greater…
To assess the effect of dietary lipids on the small intestinal microbiome in humans (proof-of-concept), the primary objective is to measure production of microbiota-derived lipid metabolites in the human small intestine after consumption of a high-…
Our primary objective of the feasibility study is to assess the acceptability and feasibility of the developed 2EAT dietary treatment in older adults with obesity. The primary objective the main study (RCT) is to investigate whether a shift towards…
Objective: The aim of the present study is to study the effect of increased adrenaline levels on the inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by administering exogenous adrenaline. Secondary aims consist of…
To establish the performance of the TouchCare Nano 14 CGM system among persons with DM.
The aim is to investigate changes in nocturnal and postprandial glucose and glycogen metabolism in individuals with IFG and IGT when compared to healthy, non-diabetic, overweight participants. In addition, it will be investigated if reducing…
To determine the mass balans after ingestion of a single dose of tagatose, a low-glycaemic sugar, in healthy volunteers.
The main objective of the 2DIAREM study is to develop minimally invasive alternatives of diabetyping. Two alternative sampling methods will be evaluated, capillary sampling and continuous glucose monitoring (CGM). Data collected through these…
The aim of this study is to compare the outcome of a clinical challenge test and home introduction of cow*s milk for children with a suspected non-IgE-mediated cow*s milk allergy. We want to evaluate the ability of both tests to determine the…
To assess the postprandial incorporation of dietary protein derived amino acids in intestinal epithelium in healthy young and older males.
To study the effects of PF-06835919 on fructose tolerance and intrahepatic lipid content in patients with HFI.
The primary objective of this study is to evaluate the efficacy of endoscopic sutured gastroplasty with the endomina device (EndoTools Therapeutics S.A.) on glycemic control (reduction in insulin dose), in obese insulin treated type 2 diabetes…
To compare the effects on glycemic control, patient reported outcomes (PRO) and experiences (PRE) of rt-CGM with FGM in a real-life outpatient setting among persons with T1D.
The aim of the present study is to assess whether the postprandial glucose response of the new test products is superior to the postprandial glucose response of an original treatment option.
The objectives of this multicenter performance evaluation study comprise an assessment of the analytical performance, the reliability and robustness of the system to obtain a CE mark.