12 results
The purpose of this observational pilot study is to evaluate the extent to which the combined glucose, heart rate, blood pressure, and other outcome patterns, collected from wearables, are associated with the severity of micro- and macrovascular…
The primary aim of this study is to determine the causal relationship between the accumulation and inflammation of perivascular adipose tissue (PVAT) and insulin-stimulated glucose uptake in skeletal muscle, measured using dynamic PET-CTA, in…
To investigate the effect of multiple sessions of whole body NMES, with or without consecutive protein intake, on muscle protein synthesis.
The primary objective is to investigate in overweight or obese older adults the effect of daily protein supplementation for two weeks with either a plant-derived protein or an animal-derived protein on vascular function and insulin-sensitivity in…
To elucidate whether reducing glycemic variability with hybrid closed-loop therapy inhibits the inflammatory response (e.g. leukocyte phenotype, cytokine production, inflammatory proteins) in people with T1DM. Our secondary objectives are to…
The primary objective is to evaluate the effect of continuing GLP-1 RA on gastric volume after standard preoperative fasting in patients using GLP-1 RA for >12 weeks. Additionally, we will evaluate the effect of withholding GLP-1 RA on…
The objective is to assess whether individuals identified with elevated Lp(a) through familial cascade screening have an increased presence of coronary atherosclerotic plaque compared to matched controls with normal Lp(a).
To establish the effect of oral inulin supplementation on continuous glucose monitoring (CGM) metrics and immunological parameters in adults with type 1 diabetes.
Primary objectivesPart 1:• To establish a corrected standardized gradient of fracture risk using the POROUS R3C ultrasound device based on prevalent fractures.Part 2:• To establish a corrected standardized gradient of fracture risk using the POROUS…
The primary objective of this study is to evaluate the diagnostic value of preselected salivary biomarkers known to be significantly elevated in individuals with obesity. This includes assessing their sensitivity and specificity to ensure their…
The objective is to investigate if AHCL in children with DM1 leads to a greater difference in BMI SDS compared to MDI. The second objective is to study if there is a difference between MDI and AHCL in DM1 regarding blood glucose regulation and…
The primary objective of the study is to assess the performance of the updated algorithm software. The secondary objectives are to assess the safety and other performance parameters of the updated software algorithm. Additionally, another secondary…