1756 results
To investigate the effect of multiple sessions of whole body NMES, with or without consecutive protein intake, on muscle protein synthesis.
The primary objective is to investigate in overweight or obese older adults the effect of daily protein supplementation for two weeks with either a plant-derived protein or an animal-derived protein on vascular function and insulin-sensitivity in…
To elucidate whether reducing glycemic variability with hybrid closed-loop therapy inhibits the inflammatory response (e.g. leukocyte phenotype, cytokine production, inflammatory proteins) in people with T1DM. Our secondary objectives are to…
The primary objective is to evaluate the effect of continuing GLP-1 RA on gastric volume after standard preoperative fasting in patients using GLP-1 RA for >12 weeks. Additionally, we will evaluate the effect of withholding GLP-1 RA on…
The objective is to assess whether individuals identified with elevated Lp(a) through familial cascade screening have an increased presence of coronary atherosclerotic plaque compared to matched controls with normal Lp(a).
To establish the effect of oral inulin supplementation on continuous glucose monitoring (CGM) metrics and immunological parameters in adults with type 1 diabetes.
The primary objective of the CONVEnIENT trial is to investigate the effect of daytime intermittent enteral tube feeding, compared to a standard continuous tube feeding pattern (24-hour/day), on glycaemic control, gastrointestinal function, circadian…
To assess the impact of short-term forearm immobilization on forearm muscle glucose uptake and amino acid net balance and kinetics of individuals with T2D compared with a control group with normoglycaemia.
To describe the natural history of coronary artery disease in patients with diabetes mellitus type 2 through the use of serial CCTA, providing a comprehensive understanding of disease progression and its clinical implications over time.
Primary objectivesPart 1:• To establish a corrected standardized gradient of fracture risk using the POROUS R3C ultrasound device based on prevalent fractures.Part 2:• To establish a corrected standardized gradient of fracture risk using the POROUS…
The primary objective of this study is to evaluate the diagnostic value of preselected salivary biomarkers known to be significantly elevated in individuals with obesity. This includes assessing their sensitivity and specificity to ensure their…
The objective is to investigate if AHCL in children with DM1 leads to a greater difference in BMI SDS compared to MDI. The second objective is to study if there is a difference between MDI and AHCL in DM1 regarding blood glucose regulation and…
The primary objective of the study is to assess the performance of the updated algorithm software. The secondary objectives are to assess the safety and other performance parameters of the updated software algorithm. Additionally, another secondary…
The objective of the study is to generate induced pluripotent stem cell lines from participants' blood in a GMP-compliant manner. These stem cells will be tested to confirm their pluripotency (having the ability to differentiate into any human…
The present study aims to compare the current clinical practice of cardiac surgery process with the introduction of a new protocol in which a preoperative iron deficiency or iron deficiency anemia is treated with 1000 mg of intravenous iron (…
The ultimate aim of this project is to answer the question whether insufficient EN should or should not be supplemented with PN early in the disease course of critical illness in children. Current medical practice and expert panels advocate the…