36 results
To assess whether a change in BMD as detected big DXA (gold standard) is comparable with the decline measured by the achilles method
To investigate the dynamic changes in bone marrow adiposity during the menstrual cycle as assessed by Dixon*s Quantitative Chemical Shift Imaging (QCSI) measurements and to determine the role of estrogen in these changes.
The objective of the study is to investigate vertebral bone marrow fat fraction and bone mineral density during surgery induced weight loss.
The aim of this trial is to study if physical performance improves and protein energy wasting decreases in patients who change from conventional hemodialysis to nocturnal hemodialysis, compared to patients who continue their treatment on…
The first objective of this study is to evaluate the effect of standard HD with different dialysate calcium concentrations as well as HD combined with citrate-acid dialysate on the clearance of CPPs and second the effect of these different solutions…
Onset of effect of systemic therapy to enhance bone density (eg, bisphosphonates) is not immediate and may not adequately protect subjects with decreased bone density from fracture.Bisphosphonate therapy will typically require 2 to 3 years of active…
We examine whether the calcium intake from food in postmenopausal women with an ID suffice to the quantity calcium intake that is advised by the NHG-standard. If the conclusion of this study will be that the population is eating less calcium than is…
The objective is to study the effect of beta-agonist and beta-antagonist treatment on human bone remodeling.
The primary objective is to assess bone structure parameters and bone strength by high resolution peripheral quantitative CT evaluation (HRpQCT) and physical activity in relation with subsequent falls, fractures and mortality in patients with a…
Fracture healing groupPrimary outcome: to study the healing of distal radius fractures in terms of calculated bone strength based on the results of cortical and trabecular bone parameters using a novel HRpQCT technique (XtremeCT device, Scanco,…
The search for correlations between components of the diet and the group has experienced a hip fracture. These findings are compared with healthy elderly. The results can contribute to nutrition -focused interventions in future studies .
The main objective is to compare the effect of immediate (or pre-existent) administration of daily calcium supplementation (1 Cacit bruisgranulaat *1000*: 1000 mg calcium) or two daily dosages of calcium + vitamin D (CaD® sachet 1000/880: 1000 mg…
The main study parameter is the routine measurement of serum phosphate concentrations after 8 and 12 weeks. Other study parameters are compliance to phosphate binders and supplement-related complaints such as nausea, diarrhoea, flushing and itchness…
Primary objective1.To determine the characteristics, frequency and severity of vascular, metabolic and hormonal side effects of angiogenesis inhibitors and EGFR inhibitors.Secondary objectives1.To investigate if steroid profile, indol profile,…
A pilot study the effect of high dose oral cholecalciferol suppletion on serum 25-OHD in elderly with osteoarthritis of the hip.
The aim of this study is to assess the sensitivity, specificity and predictive value of the Dutch osteoporosis case-finding instrument as a tool for vertebral fracture case-finding in a primary health care setting. Furthermore the impact of a…
To determine the vitamin K status in children with chronic renal failure (peritoneal dialysis patients, hemodialysis patients) and evaluate whether a correlation between bone and vascular parameters and vitamin K status exists. If vitamin K status…
The aim of this study is to determine the quantity of vitamin D3 in anterior adipose tissue in pregnant women, and to determine the influence of exposure to sunlight and the consumption of fatty fish on vitamin D storage in anterior adipose tissue.…
To study the effect of high dose oral cholecalciferol suppletion on serum 25-OHD in elderly with osteoarthritis of the hip.
The objective of this study is to assess the diagmostic accuracy of microMRI to detect ROD in children with ESRD and metabolic bone disease by oxalosis in patients suffering from oxalosis.