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Coronary Atherosclerosis in Type 1 Diabetes Mellitus

The primary objective of this study is to evaluate the coronary plaque burden and plaque characteristics in young T1DM patients as compared with non-diabetic healthy controls, using coronary computed tomography angiography (CCTA). The secondary…

Role of adrenaline in the inflammatory response in people with diabetes mellitus type 1, and healthy individuals

Objective: The aim of the present study is to study the effect of increased adrenaline levels on the inflammatory response (e.g. leukocyte phenotype, cytokines, inflammatory proteins) by administering exogenous adrenaline. Secondary aims consist of…

Magnesium Supplementation as a Strategy to Reduce Serum Calcification Propensity and Vascular Stiffness in People with Type 2 Diabetes.

To investigate the effect of daily intake of 350 milligrams of magnesium citrate oral supplementation over a period of six months on calciprotein particle maturation time (T50) in serum, a measure of calcification propensity, and on vascular…

DiEtary Sodium Intake effects on ertugliflozin-induced changes in GFR, reNal oxygenation and systemic hemodynamics: the DESIGN study, a randomized, placebo-controlled, cross-over study with ertugliflozin in people with type 2 diabetes

This study has been transitioned to CTIS with ID 2023-510257-42-01 check the CTIS register for the current data. Sodium-glucose cotransporter 2 (SGLT2) inhibitors lead to a lowering of blood pressure and confer cardiovascular and renal protection in…