120 results
1. Measurement of the 24-hour glycemic profile in response to acute submaximal hypoxic and hyperoxic exercise in order to determine its effectiveness and select the most efficient method in reducing post-exercise hyperglycemia prevalence in…
The purpose of the present study is to test whether a structured Bolus Calculation education program and subsequent use of the Accu-Chek® Aviva Expert blood glucose meter with an integrated bolus advisor can improve glycemic control in diabetes…
The primary aim of the present research is to determine if a digital health program, with information about nutrition/physical activity/diabetes and feedback on physical activity behaviour by an activity tracker leads to improvement of glycemic…
Primary objective: What are the long-term effects (i.e. after 8-week drug exposure) of the DPP-4i linagliptin versus the SU derivative glimepiride on fasting and postprandial renal hemodynamics (glomerular filtration rate (GFR)/ effective renal…
The overall objective of this study is to increase the uptake and maintenance of healthy behaviors among adults from non-Western immigrant populations who are identified as having a high risk of cardiometabolic disease after completing a health…
This study will test the following hypotheses:Primary: The DirectLife program is effective in increasing the level of physical activity in an ageing populationSecondary:1. The level of physical activity associates with parameters of 24-hour glucose…
The main objective of this study is to assess the acute effect of co-ingested vinegar on postprandial plasma glucose levels in type 2 diabetes patients.
Our main objective is to determine the effect of HO-1 induction by heme arginate infusion on insulin resistance and endothelial dysfunction related to MetS. Secondary objectives are to determine the effect on adipose tissue, adiponectin plasma level…
The objective of the study is to estimate the prevalence of (abdominal) overweight/obesitas, metabolic syndrome (and its components), and undiagnosed diabetes in the Dutch population, aged 30-69 years. Besides, differences in lifestyle (smoking and…
To investigate the potential beneficial effect of increasing protein in the diet in order to decrease hepatic lipid accumulation on a high-fat diet.
However, prior to further implementation of this programme, insight into the effectiveness is needed.Specifically, what is the effectiveness of a targeted prevention programme with regard to the prevention of DM and *in the long-term- DM-related…
The objective of this study is to develop a resistance training intervention that improves mobility and quality of life in diabetic patients. It is also our intension to achieve a better understanding of the relation between diabetic neuropathy and…
This pilot study investigates the feasability of a randomised controlled trial investigating whether the treatment of type 2 diabetes mellitus in people of 80 years and older should be retargeted to optimise quality of life instead of blood glucose…
Our aim is to compare the effect of 8-week exercise training and exercise training under hypoxia on vascular adaptations in function and structure, but also metabolic control (insulin resistance)
The objective of the study is to investigate effects of training on insulin resistance (IR), chronic heart failure (CHF) and cognition of resthome residents.
The objective of this study is to assess whether sitagliptin may prevent prednisolone-induced impairment of glucose metabolism and beta-cell function.
The effect of the dipeptide alanyl-glutamine, intravenously or enterally and perioperatively given, on postoperative insulin resistance in colon cancer patients.
The effect of NEAT or inactivity on insulin sensitivity and lipid metabolism is unclear. The objective of the present study is to evaluate the effect of 4 days of mainly sitting, or sitting and walking, or sitting, walking and biking on glucose and…
The current research proposal aims to investigate the medium and long-term health benefits of a combined supervised exercise and dietary intervention versus a dietary intervention (=usual care) in obese long-standing type 2 diabetes patients. It is…
The overall aim of the DALI study is to identify the best available measures to prevent GDM in an ongoing pregnancy, to provide a cost-benefit calculation of GDM prevention for health care systems, and to establish a pan-European cohort of mother-…