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Effect of AN-PEP enzyme on gastrointestinal breakdown of immunogenic gluten epitopes in healthy subjects

Primary: • Assess effect of AN-PEP on gluten epitope degradation in the duodenumSecondary: • Assess effect of AN-PEP on gluten epitope degradation in the stomach• Assess effect of meal caloric content on the efficacy of AN-PEP on gluten epitope…

Celiac disease: interplay between genes and the environment. Towards the unraveling of disease initiating events.

The primary oblective of the study is to elucidate all molecular mechanisms leading to coeliac disease.In order to establish the scientific basis for the development of improved diagnostics, novel therapies and safer foods for patients, in the CDC:…

Nutrition to Relieve IBS symptoms by targeting the Microbiota

The primary objective is to determine the bifidogenic effects of a 4-week intervention with one of four dietary supplements (Chondroitin sulfate, NOVELOSE® 3490, and Pea Fiber, and Lactium®) in IBS patients. The secondary objective is to determine…

The effect of lactose consumption in lactase non-persistent individuals on gut microbiota

The primary objective of this study is to assess whether repetitive consumption of an increasing dose of dietary lactose in LNPers induces colonic microbial adaptation by a shift in microbiota composition and functional potential as measured with…

Proof of concept clinical trial of safety and biological activity of Bifidobacterium Longum NCC 2705 in gluten sensitivity

The primary objective is to evaluate in the two targeted populations (i.e. CD and self-reported NCGS subjects):1) the safety profile of BL NCC 2705 2) the gastro-intestinal (GI) tolerability of BL NCC 2705