36 results
To answer the question if dried blood spot (DBS) analysis and saliva hormone testing are reliable methods to determine the concentration of NGF-ß in healthy subjects.
The main goal of this technical feasibility study is to investigate with which HPV isolation and detection method urine and the Evalyn Brush can be combined. HPV stability in urine and on the Evalyn Brush will be investigated as it*s unclear how…
The objective of this study is to statistically identify the optimal level of contact-pressure for DBT. *Optimal* is defined as a weighed sum of three clinical interests: as high as possible lesion conspicuity, as low as possible absorbed glandular…
Primary Objective: To study long-term effects of premenopausal risk-reducing salpingo-oophorectomy (RRSO) on - cardiovascular status- bone mineral density- cognitionSecondary Objective: To study long-term effects of premenopausal RRSO on - quality…
Primary objective: to improve participants* quality of life, as measured by the SF-12 general health domain, by actively engaging in a prostate cancer diet. Secondary objectives: - To improve participants* feeling of being in control of their…
primary objective:To evaluate the effect of individualised FE 999049 treatment on ovarian response in a long GnRH agonist protocol versus a GnRH antagonist protocolSecondary objectives:* To evaluate the effect of individualised FE 999049 treatment…
The primary objective of this study is to compare overall survival (OS) in patients with progressive PSMA-positive mCRPC who receive 177Lu-PSMA-617 in addition to best supportive/best standard of care versus patients treated with best supportive/…
To compare the effects of LNG-IUD (Mirena® of Kyleena®) versus Cu-IUD (T-Safe® or Multi-Safe®) on mental well-being and quality of life.
The primary objective is efficacy of atezolizumab in advanced penile cancer patients measured by progression-free survival.
To assess platelet function and coagulation parameters in adult chronic ITP patients in relation to their bleeding phenotype
This study has been transitioned to CTIS with ID 2024-510605-28-00 check the CTIS register for the current data. Primary Objective• To compare the progression free survival (PFS) of programmed death-ligand 1 (PD-L1) positive patients with Stage III…
In this study, we evaluate the efficacy of a sexual rehabilitation programme in improving the sexual functioning of women who are treated with radiotherapy for gynaecological cancer. The rehabilitation programme is compared to optimal regular care (…
The goal of this study is to elucidate whether there is a difference in endometrial parameters (determining endometrial receptivity) between women with reproductive failure: RIF and RM. Secondly we will investigate how the endometrial parameters of…
The primary objective of this study is to prove feasibility and safety of TPLA for LUTS due to BPO in healthy men. The secondary objectives are to determine functional voiding, erectile outcomes and changes on imaging.
The purpose of this study is to understand if a new treatment for prostate cancer (niraparib) added to a standard treatment (abiraterone acetate plus prednisone) will work better than the standard treatment alone.Cohort 3: the purpose is to evaluate…
The OPTIMUM-study aims to gain insight into the optimal timing and method for promoting sustained adherence to lifestyle and body weight recommendations in PMBC survivors.The aim of the extra measurement during the second COVID-19 lockdown is to…
1) What is the variation in follow-up care practice since 2011 for cervical cancer patients?2) What physician-, patient- and informal caregiver -factors are associated with differences in follow-up care schedules? Regarding patient/ informal…
Primary Objective: This study aims to comprehensively compare the effectiveness and costs of perioperative topical oestrogen for postmenopausal women undergoing POP surgery. In this trial, the perioperative use of oestrogen is considered superior to…
Primary: To evaluate the sensitivity and specificity of dynamic contrast enhanced (DCE-MRI) to identify patients who have increased risk of disease recurrence (local, nodal, systemic) after radio-chemotherapy of cervix cancer.Secondary: To apply…
To investigate the technical feasibility of inserting a brachytherapy needle into the prostate to a defined tumour target point using a robotic device.