27 results
To increase our understanding of the developmental significance of chromosomal mosaicism in preimplantation embryos by investigating their implantation potential and the fate of abnormal cells after an in vitro implantation procedure.
1) To assess the antitumor activity of PHA-739358 administered as IV infusion according to two different dose schedules in metastatic HRPC patients progressing on standard docetaxel-based chemotherapy.2) To have a precise idea of the antitumor…
The primary aim of the phase I part of this trial is to establish the safety of a split dose regimen of Re-188-HEDP . The primary aim of the phase II part of this trial is to obtain insight in the efficacy of a split dose regimen of Re-188-HEDP , as…
The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.
The objective of the study is to examine the opinion of women about the accuray of frozen section diagnosis. A important question is how women feel about a second operation in case of a false negative testresult.
The objective of this study is to evaluate a new and less invasive method of PGS. The new PGS technique will analyse a nucleus of a blastomere that was obtained by nuclear extraction rather than by biopsy of a whole blastomere.
1. To prevent multiple pregnancies and the concomittant neonatal mortality and morbidity while retaining acceptable delivery rates in couples with unexplained subfertility or mild male subfertility and poor fertility prospects. 2. To assess the…
To compare the present gold standard for measuring genital blood flow in humans (for men: a mechanical penile strain gauge (Barlow-gauge) , for women: vaginal photoplethysmography) with infrared technology.
In this study we aim to compare the effect of two different ovarian stimulation protocols on embryo quality in a group of women of 39 years or younger, in a prospectively randomized controlled trial. PGS will be performed to assess chromosomal…
To test the value of preoperatively performed urodynamics with regard to outcome of surgery for stress urinary incontinence (SUI) and to examine whether not performing urodynamics preoperatively is more cost effective than performing urodynamics…
The aim of this study is to get insight into bioavailability of selenium in prostate tissue and changes of gene expression profiles that might be responsible for selenium-induced chemoprevention. To meet this objective, the relationship between…
To evaluate the impact of treatment of undetected, asymptomatic, predefined uterine abnormalities on the success of IVF treatment
1. We will explore the feasibility of homeopathic treatment with a semi standardised homeopathic prognostic treatment protocol for PMS in daily homeopathic practice. 2. We will evaluate the prognostic validity of using a semi standardised prognostic…
1. determine how many male patients visiting the OPD urology for LUTS and/ or ED lack a certain amount of physical activity2. measure the willingness of those patients to follow a program for increasing their physical activity3. discover factors…
1. Investigate the effects of gynecological pelvic surgery on vaginal innervation, vaginal vascularisation and pelvic floor tonus. 2. Investigate the effects of gynecological pelvic surgery on sexual and psychological well-being. 3. Investigate the…
Ultrasonography shows a niche at the site of the uterine caesarean scar in the majority of women with a CS in the past history. A niche is a triangular, anechoic area at the presumed site of incision. Our primary objective is to develop an…
The overall aim of this study is to examine, in adult female CCS in the Netherlands, the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment, on: 1…
It is important that we get insight into which of the above mentioned factors are related to psychological problems. It could give us some important starting points for designing psychological intervention programs. Such an intervention could not…
The aim of the study is to prospectively evaluate the accuracy of integrated whole body positron emission tomography/computed tomography (PET/CT) in staging patients with primary ovarian cancer, with use of histological findings as the reference…
To study long term results of hypospadias surgery in childhood