29 results
To explore the extent of inter- and intrafraction anatomical changes of the tumour and surrounding normal tissues, throughout the full course of treatment, and to subsequently assess the impact of these changes on the nominal planned dose. This…
Objective: The primary goal of the current study is to study the immunogenicity and safety of HPV vaccination in patients with an autoimmune disease. Based on retrospective analysis with other vaccines we hypothesize that patients with autoimmune…
To investigate the hypothesis that women with uterine prolapse stage 2 or more treated by laparoscopic sacrohysteropexy will have equal or lower recurrence rate of prolapse compared to women treated by vaginal sacrospinous hysteropexy.
In this controlled (studygroups from P05-095 will serve as controls) observational study, the effects of radiation therapy after nerve-sparing radical hysterectomy for early stage cervical cancer on sexual function, bladder and bowel function is…
The primary objective is to assess the differences in mobility of pelvic organs between three commonly performed treatment options for uterine descent (vaginal hysterectomy, vaginal sacrospinous hysteropexy and laparoscopic sacrohysteropexy). The…
This study is designed to determine the usability of the CollaGUARD adhesion barrier in gynecological surgery. The aim is to collect qualitative and quantitative data in a small number of subjects (pilot study) to gain information on the usability…
The objective of the MINI-trial is to compare the clinical effectiveness, quality of life, and cost-effectiveness of uterine artery embolisation (UAE) to MR guided focused ultrasound (MRgFUS) in pre- or perimenopausal women with symptomatic uterine…
To investigate the hypothesis that women with uterine prolapse stage 2 or more treated by sacrospinous fixation have equal or lower recurrence rate of prolapse than women with a vaginal hysterectomy.
To increase progression-free survival at 3 months.
The primary objective of this study is to evaluate feasibility of performing MR-HIFU treatment of uterine fibroids in a Philips Sonalleve MR-HIFU system equipped with a Direct Skin Cooling device. Secondary objective is evaluation of safety.
To evelauate the clinical efficacy after 12 months using a composite outcome: absence of apical prolapse (st 0 or I), absence of bulge symptoms, and absence of reintervention in the treated vaginal compartments (apical and anterior)
The primary objective of this study is to evaluate the anatomical success of the GYNECARE PROLIFT + M* system in women with symptomatic ICS POP-Q Stage III or IV, requiring surgical correction of pelvic organ prolapse (POP). Secondary objectives…
In this study we want to evaluate the safety, technical efficiency, and volume treatment capabilities of the Philips MR guided HIFU system in the treatment of patients with symptomatic uterine fibroids. This information is required for CE labelling…
To compare sexual functioning and complaints concerning micturation and defecation in women after abdominal or vaginal trachelectomy for early stage cervical cancer.
The objective of the project is to study the effect of conservative, non-surgical treatments of pelvic organ prolapse in a randomized clinical trial. The treatments under study, pessaries and pelvic floor physiotherapy, aim at reducing the symptoms…
Long-term evaluation of efficacy and safety of the AMS Pelvic Floor Repair System devices for prolapse repair
To determine the optimal moment to start bladder training after vaginal prolapse surgery with anterior colporrhaphy.
Determination of tissue perfusion and dielelectric properties by MRI in women with cervical cancer.
To evaluate the duration of admission, feasibility, patient satisfaction and complication rate of vNOTES hysterectomy with BSO and compare it with laparoscopic hysterectomy with BSO in case of clinical stage 1 low grade endometrial cancer.
What is the effectiveness of at-home yoga-intervention for women suffering from pain due to endometriosis when compared to no yoga intervention.