56 results
Aim of the Study:This prospective, single-arm study is to evaluate the mid-term efficacy and safety of the Calistar S pelvic floor repair system for prolapse repair.
The ultimate objective is to optimize pessary treatment for all patients with pelvic organ prolapse (POP). To reach this goal, we need to learn more about the mechanisms behind success and failure of pessary treatment. Previous research suggested…
Investigation of pelvic blood circulation by MRI in women with a gynaecological cancer who will have curative radiotherapy with or without weekly HT for inoperable pelvic tumours.
Primary Objective: Validation of the response prediction algorithm to hormonal therapy defined as response rate, progression free survival (PFS) and clinical benefit rate (CBR). Secondary Objectives: • Health-related quality of life in patients with…
Current performance of biomarker signatures for non-invasive diagnosis, based on endometrial and blood samples combined with an algorithm, are the following (determined during previous studies): Sensitivity Specificity PPV NPV EndoSearch…
1. To asses non-inferiority of BSC mesh in surgical success (= anatomic cure, subjective improvement and no re-treatment necessary) in the treatment of apical prolapse compared to unilateral SSLF at 12 months;2. Improvement of quality of life…
To evaluate the efficacy of intrauterine application of MateRegen®Gel, a crosslinked hyaluronan gel, in reducing the formation of postoperative intrauterine adhesions after NovaSure ablation.
Primary Objective: * To evaluate the presence and time of occurrence of a niche in women who underwent a caesarean delivery Secondary Objective(s): * To evaluate changes of niche size and thickness of the residual myometrium over time* To determine…
The primary objective of this phase 2 study in patients with advanced endometrial cancer is to compare the clinical efficacy of MLN0128 + weekly paclitaxel to weekly paclitaxel alone in second- or third-line treatment of advanced, recurrent, or…
What is the effectiveness and cost-effectiveness of surgical treatment of women suffering from pain due to an endometrioma when compared to treatment with medication?
To determine whether cine-MRI is able to assess the so-called *sliding viscera* sign in the posterior compartment, an known sonographic indicator for the absence of POD adhesions.
An explorative study, that will include 15 patients and 15 volunteers without pelvic floor disorders, will be conducted to evaluate the possibilities of an open 0.25T MRI- system to assess the pelvic floor and to get a better understanding of the…
To evaluate long-term outcome (3-10 years) in terms of quality of life, subjective and anatomic failure and erosion after laparoscopic versus open abdominal sacrocolpopexy as a treatment for vaginal vault prolapse in patients with a history of…
The aim of this study is to optimize patient selection, to improve treatment efficacy and to better visualize treatment outcome. The objectives of this study will be investigated using the same patient population. For the main endpoints we…
Primary Objective: To study the effect of different treatment approaches - existing of conservative management, pharmacological treatment and surgical treatment - on sexual function in patients diagnosed with endometriosis. Secondary Objective(s):…
The use of an interactive web-based Decision Aid reduces decisional conflict and increases patient satisfaction with information and care.