66 results
Does the installation hyaluronic acid (hyalobarier ® Gel Endo), in patients with M. Asherman reduces or prevents the incidence and severity (ESGE score/classification) of spontaneous recurrence of adhesion better then the IUD without Cu or hormones…
To evaluate the duration of admission, feasibility, patient satisfaction and complication rate of vNOTES hysterectomy with BSO and compare it with laparoscopic hysterectomy with BSO in case of clinical stage 1 low grade endometrial cancer.
This protocol describes a framework that will be used to create multiple studies, which are based on the secondary objectives. The outcomes of the studies together will provide more insight in the primary objective. Primary Objective: Investigate…
The objective of the present study is to evaluate the safety of Womed Leaf after hysteroscopic myomectomy and its potential efficacy in preventing IUA at second look hysteroscopy.
Objective: This protocol describes a framework that will be used to create different studies. The general primary and secondary objectives of this protocol are stated below:Primary objective: Investigate the effect of surgery on the position and…
This study has been transitioned to CTIS with ID 2023-506551-23-00 check the CTIS register for the current data. This study has two parts. The purpose of the first part of the study is to investigate if the investigational drug called dostarlimab (…
What is the effectiveness of at-home yoga-intervention for women suffering from pain due to endometriosis when compared to no yoga intervention.
To determine the long-term (cost)effectiveness of Magnetic Resonance image guided High Intensity Focused Ultrasound (MR-HIFU) compared to standard (minimally) invasive fibroid care in-cluding UAE, myomectomy and hysterectomy.
Aim of the Study:This prospective, single-arm study is to evaluate the mid-term efficacy and safety of the Calistar S pelvic floor repair system for prolapse repair.
The ultimate objective is to optimize pessary treatment for all patients with pelvic organ prolapse (POP). To reach this goal, we need to learn more about the mechanisms behind success and failure of pessary treatment. Previous research suggested…
Investigation of pelvic blood circulation by MRI in women with a gynaecological cancer who will have curative radiotherapy with or without weekly HT for inoperable pelvic tumours.
Primary Objective: Validation of the response prediction algorithm to hormonal therapy defined as response rate, progression free survival (PFS) and clinical benefit rate (CBR). Secondary Objectives: • Health-related quality of life in patients with…
Current performance of biomarker signatures for non-invasive diagnosis, based on endometrial and blood samples combined with an algorithm, are the following (determined during previous studies): Sensitivity Specificity PPV NPV EndoSearch…
Primary objective: to study the (cost) effectiveness of applying the 4DryField barrier on the uterine scar after a caesarean delivery, in the prevention of adhesions, niche development and related gynecological symptoms. Secondary objectives: to…
1. To asses non-inferiority of BSC mesh in surgical success (= anatomic cure, subjective improvement and no re-treatment necessary) in the treatment of apical prolapse compared to unilateral SSLF at 12 months;2. Improvement of quality of life…
To evaluate the efficacy of intrauterine application of MateRegen®Gel, a crosslinked hyaluronan gel, in reducing the formation of postoperative intrauterine adhesions after NovaSure ablation.
Primary Objective: * To evaluate the presence and time of occurrence of a niche in women who underwent a caesarean delivery Secondary Objective(s): * To evaluate changes of niche size and thickness of the residual myometrium over time* To determine…
The primary objective of this phase 2 study in patients with advanced endometrial cancer is to compare the clinical efficacy of MLN0128 + weekly paclitaxel to weekly paclitaxel alone in second- or third-line treatment of advanced, recurrent, or…
What is the effectiveness and cost-effectiveness of surgical treatment of women suffering from pain due to an endometrioma when compared to treatment with medication?
We want to stuudy if exogenous hormone administration (oral administration of estrogen and gestagen) starting immediately after successful hysteroscopic adhesiolysis, in patients with M. Asherman reduces or prevents the incidence and severity (ESGE…