29 results
In our previous studies using optical spectroscopy, both ex vivo and in vivo, most promising results were obtained for tissue diagnosis. Moreover, invasive procedures for biopsy or radiofrequency ablation in these tissues are all very common. Thus,…
The principal objective of the study is to determine if the performance of the new technique (magnetic tracer and magnetometer) is equivalent to the performance of the standard technique (patent blue dye and radioisotope, wire localization).The…
To test the feasibility of breast MR elastography and explore the viscoelastic parameters of (1) normal breast tissue, of (2) breast tumours and of (3) scar tissue in the breast after lumpectomy.
In breast-conserving surgery, there is evidence that approximately 30% of women receive a suboptimal or poor aesthetic outcome; however there is currently no standardised method of identifying these women.The PICTURE project aims to address these…
Up front breast surgery in patients with primary distant metastatic breast cancer, will result in an improvement of the 2-year survival compared to the survival achieved with systemic therapy and delayed local treatment or systemic therapy alone.The…
Primary goal: determine the diagnostic quality of CE-MRI scans acquired in supine positionSecundary goal: determine the accuracy of deformable image registration between prone CE-MRI and non-CE-MRI in supine position as an alternative option
The PICTURE project aims to address these issues by providing objective tools, tailored to the individual patient, to predict the aesthetic outcome of local treatment. Using a combination of 3D photography and routinely acquired radiological images…
Primary Objective: Examining the value of ABVS in relation to current breast imaging techniques by: - comparison of ABVS findings with MRI findings. - comparison of ABVS findings with mammography and hand-held US. Secondary Objectives: - assessment…
Aim of this study is to confirm the results from ex vivo research in humans in a clinical setting. The objective is to perform optical spectroscopy measurements during surgical procedures in vivo, involving resection of either breast, liver or lung…
Primary objective:To establish the accuracy of pretreatment 7T MRI to identify low-risk breast cancers. This will be done by identifying preoperative imaging-based characteristics related to risk factors of cancer relapse in the resection specimens…
To evaluate the effect of HSP90 inhibition by AUY922 on VEGF by means of 89Zr-bevacizumab PET. Primary endpoint: measurement of decreased VEGF compared to baseline. A decline is defined as a decrease of at least 30% in mean Standardized Uptake Value…
To show the effect of the HSP90 inhibitor AUY922 on HER2 expression by means of 89Zr-trastuzumab PET scanning. Primary endpoint: measurement of decreased HER2 expression compared to baseline. A decline is defined as a decrease of at least 30% in…
a) to analyze and optimize the image quality of this prototype 3D-scanner. b) to assess the potential of the 3D-scanner to detect lesions (benign and malignant) in the breast and c) to assess the potential to determine the localization of lesions in…
The main objective of this study is to determine the performance of whole breast scanning with ultrasound (WBUS), combined with MRI, in a yearly breast cancer screening program for high-risk women, compared to the current practice of the combination…
To identify the determinants of psychological vulnerability through time (for the development of the prognostic risk profiles)
This study aims to develop a prediction rule for PMPS one year after breast surgery based on neurophysiological, psychological, and clinical parameters. Based on this prediction, individualized perioperative management and postoperative revalidation…
Primary goal: to assess the accuracy of a supine magnetic resonance imaging (MRI)-guided electromagnetic navigation system used for tumor marker implantation in breast cancer patients.Secondary goal: to assess the variability in target volume…
Primary Objectives: 1) Is it feasible to implement plane-wave imaging in a combined DBT-US device to decrease scan time while preserving or improving image quality compared to conventional imaging? 2) How do DBT images compare obtained by DBT with a…
The main objective of this project is to demonstrate the feasibility of DLSCT to detect breast cancer in women with dense breasts.
The purpose of the study is to provide comparative analysis of breast imaging modalities of BCT (nu:view) compared to MRI.