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The effects of a yoga-based stress reduction program on fatigue and quality of life in women with chemotherapy for breast cancer: a mono-centre, pragmatic, randomized clinical study

To investigate whether an adjunctive YBSR program added to standard care compared to standard care alone, can reduce:1.fatigue symptoms (primary objective)2.psychological distressand improve:3.health-related quality of life4.sense of coherence5.…

Molecular studies on reduced ovarian reserve and embryo competence in BRCA1/2 mutation carriers

Investigate the association between BRCA1/2-mutations, DNA damage, apoptosis and oocyte/embryo quality in immature germinal vesicle (GV) bearing oocytes, immature metaphase 1 (MI) and unfertilized mature metaphase 2 (MII) oocytes and affected early-…

Tailored compression and pain experience in mammography

The aim of the research up till now was, during a number of months, to examine a total of 500 participants referred for mammography to the AMC. The different parameters which are relevant to compression were measured. Particularly the influence of…

Informing relatives about their cancer risk and preventive measures. A trial to assess the effectiveness of additional counseling.

The aim of this study is to evaluate an intervention aimed at improving family disclosure of inherited cancer risks by 1) supporting counselees in what they experience as a necessary, but at times difficult, task and, consequently 2) provide more at…

Unravelling brain mechanisms of cognitive impairment in breast cancer patients during adjuvant endocrine treatment

Primary Objective: Does long-term endocrine adjuvant treatment for breast cancer lead to structural changes in the brain and to functional changes in brain-wide networks, and do these changes correlate with cognitive impairment induced by the…

The impact of reconstructive breast surgery on the risk of developing lymphedema

Our primary objective is to determine the effect of breast reconstruction on the risk of developing lymphedema. Secondarily, we will look at lymphedema and the correlation with 1) primary and secondary breast reconstruction, 2) the extent of…

The influence of pressure instead of force on the compression procedure of breasts during mammographic examinations.

The aim of the research is during a period of three months, to examine a total of 500 participants referred for mammography to the AMC. The different parameters which are relevant to compression will be measured. Particularly the influence of…

The psychosocial determinants of stress(vulnerablity) and cognitive complaints in breast cancer patients receiving elective radiotherapy

The primary aim of this study is to identify the psychosocial determinants of stress (vulnerability) and cognitive complaints in breast cancer patients treated with adjuvant radiotherapy. The stress model of Taylor and Aspinwall will be used.

The incidence of pulmonary embolism in patients undergoing abdominal flap breast reconstructions, a prospective study.

The primary aim of this study is to prospectively assess the incidence of pulmonary embolism in patients undergoing abdominal flap breast reconstruction.

The Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion

To set up a cohort of breast cancer patients, collecting information on patient characteristics, short and long-term clinical and patient reported data, and to compare outcomes with a healthy refrence population. whichThe cohort will also serve as…