68 results
the aim of this prospective cohort study is to investigate the difference in quality of life and satisfaction with cosmetic result in patients with breast cancer undergoing breast conserving therapy surgery versus patients undergoing breast…
Primary goal: to assess the accuracy of a supine magnetic resonance imaging (MRI)-guided electromagnetic navigation system used for tumor marker implantation in breast cancer patients.Secondary goal: to assess the variability in target volume…
The aim of this pilot study is to study if there is an effect on pain, QoL and the amount of breast edema of wearing a compression vest, in order to determine whether a large randomized study is feasible.
The objective of this study is to statistically identify the optimal level of contact-pressure for DBT. *Optimal* is defined as a weighed sum of three clinical interests: as high as possible lesion conspicuity, as low as possible absorbed glandular…
The overall study aim is to determine the efficacy rate of complete ablation for the most promising types of thermal ablation (RFA, MWA or CA) technique for patients with early stage breast cancer (cT1N0M0) without an extensive component of DCIS (…
Primary Objectives: 1) Is it feasible to implement plane-wave imaging in a combined DBT-US device to decrease scan time while preserving or improving image quality compared to conventional imaging? 2) How do DBT images compare obtained by DBT with a…
The main objective of this project is to demonstrate the feasibility of DLSCT to detect breast cancer in women with dense breasts.
The purpose of the study is to provide comparative analysis of breast imaging modalities of BCT (nu:view) compared to MRI.
The main objective of this study is to demonstrate treatment efficacy of MR-HIFU ablation of breast cancer. Effective treatment is defined as 100% necrosis of the targeted primary breast tumor. The secondary objective is safety of the MR-HIFU…
The OPTIMUM-study aims to gain insight into the optimal timing and method for promoting sustained adherence to lifestyle and body weight recommendations in PMBC survivors.The aim of the extra measurement during the second COVID-19 lockdown is to…
To assess whether HBOT reduces pain, and improves physical functioning and QoL in breast cancer patients with late radiation toxicity.
The main goal is to show in postmenopausal estrogen receptor positive breast cancer patients the influence of:Microbiota composition and ß-glucuronidase activity on systemic endoxifen levels during tamoxifen therapy.
Early detecction of breast cancer in women with high risk of developing breast cancer with protein and glycan biomarkers.
To set up a cohort of breast cancer patients, collecting information on patient characteristics, short and long-term clinical and patient reported data, and to compare outcomes with a healthy refrence population. whichThe cohort will also serve as…
In this feasibility study, we will validate the value of the preoperative [89Zr]trastuzumab PET/CT imaging to identify HER2 positive primary breast cancer and the possibility to predict pathological complete response.
Primary Objective: To study the feasibility of Velocity Selective Arterial Spin Labeling as a non-invasive technique for breast cancer screening by comparing image quality with DCE-MRI.Secondary Objectives: Comparing tumor characteristics and…
This study has been transitioned to CTIS with ID 2024-511096-15-00 check the CTIS register for the current data. To assess the safety and tolerability of adjuvant treatment with olaparib
The primary objective is to investigate if thermal ablation of breast tumors less than 2cm with < 25% DCIS is effective in terms of the number of tumors in which complete ablation is found on pathology result.
First, the threshold for the biomarkers of 31P-MRS will be determined. These biomarkers can indicate whether a patient with breast cancer benefit from the neoadjuvant chemotherapy (NAC). Then it is determined whether a (combination of) biomarker(s)…
The primary objective of the study is to assess the incidence of pathological complete response (pCR) in breast and ipsilateral axillary tissue after daily treatment with veliparib in combination with neoadjuvant carboplatin and paclitaxel followed…