16 results
The primary objective is to investigate the quality (whether assessable by a pathologist or not) of the endometrial sample obtained by aspiration when performed directly before or after the SIS in postmenopausal women. Secondary objectives are to…
Primary objective: To confirm that a BRCA-mutation is a determinant of advanced ovarian ageing by using serum-AMH as ovarian reserve test.Secondary objective: To confirm that a BRCA-mutation is a determinant of reduced reproductive health/outcome.
To evaluate the prevalence of advanced ovarian ageing in cycling DM-1 patients using ovarian reserve (OR) testing. To assess the mean age at natural menopause and its variation in DM-1 patients. To study the role of vascular factors in relation to…
To examine the long-term effects of a CT- and/or RT-induced premature menopause on BMD, cardiovascular status, neurocognitive function and QoL in female HL survivors.
The aims of this prospective study are to investigate:1a: Changes in menopausal symptoms and biochemical changes as result of PBSO in premenopausal women.1b: Changes in menopausal symptoms and biochemical changes as result of PBSO in postmenopausal…
The proposed study will evaluate the efficacy of a supportive intervention program in alleviating menopausal symptoms, improving sexual functioning and enhancing the quality of life of younger women (< 50 years) with breast cancer who have…
SIS and hysteroscopy in the work-up for postmenopausal bleeding will be studied. Cost en medical effectiveness in terms of treatment of the postmenopausal bleeding will be evaluated. To assess which women need saline-infused sonography and/or…
The proposed study will evaluate the efficacy of a supportive intervention program in alleviating menopausal symptoms, improving sexual functioning and enhancing the quality of life of younger women (< 50 years) with breast cancer who have…
Primary objectiveIs RRSO at age <= 45 in BRCA1/2 mutation carriers a risk factor for development of subclinical atherosclerosis, independent of traditional cardiovascular risk factors? Secondary objectiveAre menopausal symptoms in BRCA1/2…
Primary Objective: To study long-term effects of premenopausal risk-reducing salpingo-oophorectomy (RRSO) on - cardiovascular status- bone mineral density- cognitionSecondary Objective: To study long-term effects of premenopausal RRSO on - quality…
Objective: Evaluate uterine contraction features (frequency, amplitude, direction, and coordination) using a dedicated speckle-tracking algorithm by 2D transvaginal ultrasound measurement in postmenopausal women presenting with vaginal bleeding or…
The primary objective is to evaluate the reproducibility of the Corneometer® as a measurement instrument to quantify hydration of the vaginal wall, evaluated by intra- and interobserver variability. The secondary objective is to measure the response…
To evaluate RRS after childbearing with delayed RRO as an alternative for RRSO in BRCA1/2 gene germline mutation carriers. We hypothesize that delay of menopause leads to an improvement of quality of life and sexual functioning, and a decrease in…
Elinzanetant is an investigational compound. It is not approved for sale. That means it can only be used in studies like this one. Elinzanetant has been extensively tested in the laboratory. It has also been already administered to approximately 300…
Progesterone for Breast Development in Trans Women; Assessment of effects and safety -a pilot trial-
To explore the effects on breast development of addition of progesterone to the treatment with estradiol in trans women after vaginoplasty or orchiectomy. Secondary objectives include safety and patient satisfaction, mood, and sleep.
To demonstrate the presence of a reduced age specific ovarian reserve status in BRCA mutation carriers by:1. using serum AMH as ovarian reserve status test. 2. using the antral follicle count (AFC) as ovarian reserve test3. using ovarian response to…