35 results
Primary objective: 1) To examine the effect of IGSF1 deficiency syndrome on semen quality when compared to WHO reference ranges;2) The comparison of semen quality of these patients to that of healthy controls.To investigate the association between…
In view of this lack of evidence and strong practice variation we propose a randomized clinical trial in overweight and obese subfertile women, in which we compare the costs and effects of a six months structured lifestyle program, aimed at weight…
The overall objective of this study is to examine specific cardio-metabolic and cardiovascular parameters in women of subfertile couples. This study protocol is divided in 3 studies to evaluate several cardio-metabolic/cardiovascular parameters in…
This large prospective multi-center cohort study aims to identify patient*s characteristics that significantly influence ovarian response to mild stimulation with a fixed dose of 75 IU recombinant FSH
Objectives: The purpose of this study is to assess the costs and effects of THL compared to HSG in a large randomized controlled trial.
To asess whether the Chlamydia Antibody Test (CAT), used to determine the presence of antichlamydia IgG antibodies in serum for diagnostics in the fertility clinic, can serve as an intermediate marker for PID/tubal pathology caused by Chlamydia.
To test The Selection Failure hypothesis by assessing A) the degree of embryo invasiveness and decidual acceptance (the quality of decidualization, endometrium-embryo communication and endometrial stromal cell (ESC) migration) and B) the angiogeneic…
We will investigate whether Chlamydia IgG antibody presence and titers in vaginal swabs (mucosa-CAT) are comparable to antibodies found in serum (serum-CAT), and as such could serve as a marker for a past Chlamydia infection with an enhanced risk of…
We aim to: 1) Characterize differences between paternal and maternal chromatin organization and pericentric heterochromatin formation after fertilization and during pre-implantation embryo development. 2) Analyze if this asymmetry affects formation…
To determine wether a HyFoSy is a less painful procedure compared to a HSG examination for tubal patency testing
The present study is designed to validate the Dutch IIEF. The psychometric properties of the Dutch version of the IIEF will be investigated.
The primary aim of this study is to examine/determine the effect of Totally ExtraPeritoneal (TEP) endoscopic hernia repair on male fertility. To measure this outcome, we examine testicular perfusion, volume, semen quality and blood levels of…
The primary aim is to evaluate sexual function in adults with congenital colorectal disease and sacrococcygeal teratoma. The secondary aim of this study is to evaluate whether additional information and care on this subject has been missed and would…
To determine the value of a post coital test in the basic fertility work up in WHO class II subfertile women ovulatory after clomiphene citrate (CC).
Primary objective:To evaluate variations of androgenicity and androgen (re) activity in (apparently) eugonadal females by using CAG repeat length polymorphism ([CAG]n) of the androgen receptor, free testosterone levels, 2D:4D ratio and attention for…
Comparing fertilty of male galactosemia patients to a control group
To determine whether flushing of the fallopian tubes is more effective with an oil based contrast medium or a water based contrast medium in terms of ongoing pregnancy.
The objective of this study is to evaluate a new and less invasive method of PGS. The new PGS technique will analyse a nucleus of a blastomere that was obtained by nuclear extraction rather than by biopsy of a whole blastomere.
To study the effect of peginterferon alpha and ribavirin on spermatozoa
Objectives1. To assess the prevalence of sexual dysfunction in a Dutch cohort of female childhood cancer survivors.2. To assess the disease-associated risk factors for sexual dysfunction (type of treatment, age at treatment) in female childhood…