22 results
To investigate whether it is possible to manipulate perfusion in type 3 fibroids with MR-HIFU.
- To assess the effect of QBW251 on the pharmacokinetics of a monophasic combined oral contraceptive containing 30 µg ethinyl estradiol (EE) and 150 µg levonorgestrel (LVG).- To assess the effect of QBW251 on the pharmacodynamics of a monophasic…
In this randomized study, timing during (day 1-7 of the menstruation cycle WITH vaginal blood loss) or beyond menstruation (in menstruation cycle day 8 and further WITHOUT vaginal blood loss) will be compared regarding differences in patient-…
To obtain the safety and effectiveness data necessary to support a Premarket Approval (PMA) Application to the U.S. Food and Drug Administration (FDA)
- To establish the bioequivalence of the hormones norgestimate, norelgestromin, and ethinyl estradiol in NGM/EE Schaffhausen tablets compared with the same hormones in NGM/EE Manati tablets.- To assess the safety and tolerability of both…
The objective of this study is to establish the effectiveness and confirm the safety of the VizAblate System in the ablation of large (> 5 cm) symptomatic uterine fibroids.
Our primary objective is to study the effectiveness of hysteroscopic resection for niche related uterine bleeding disorders. The procedure will be performed in small niches with a residual myometrium of more than 3mm.Our secondary objective is to…
The primary objective of this study is to evaluate the safety and effectiveness of Doppler guided Uterine Artery Occlusion (D-UAO) as treatment for the reduction of fibroid-associated symptoms.
To study if a hysteroscopic resection a safe and effective treatment is for intermittend/post menstrual bloodloss or spotting.
This study primarily aims to get insight in the intraoperative nociceptive state of the patient as an index of the amount of pain stimuli comparing the three modes of hysterectomy. Next to this, by measuring pre-, intra- and postoperative stress…
To establish the safety and effectiveness of the Sonata System in the treatment of symptomatic uterine fibroids.
Is hysteroscopic resection of submucous myomas under procedural sedation with propofol (PSA) in an outpatient setting a cost-effective alternative for hysteroscopic myomectomy performed under general anesthesia in the operation room?
The aim of this research is to test the efficacy and safety of a new microcatheter 2.8F Sequre for treatment of uterine fibroids and/or adenomyosis with a standard embolization technique and to demonstrate the added value of this catheter, namely to…
This study aims to create an indication of the effect size during and after adherence to the low FODMAP diet to calculate a sample size for a future RCT on this subject.
To study if an online brief CBT intervention is effective for anxiety and depression compared to care as usual (CAU) in patients with PCOS
Primary ObjectiveTo evaluate the safety of the Aqua Therapeutics Thermal Therapy Vapor Ablation System (ATTTVAS).Secondary Objectives1. To evaluate the change of menstrual blood loss (MBL).2. To evaluate the effect of MBL on the quality of life (QoL…
The primary objective of this study is to assess the efficacy and safety of vilaprisan in subjects with uterine fibroids compared to ulipristal. The secondary objective of this study is to evaluate the efficacy and safety of different treatment…
To investigate the potential of atosiban as a treatment for pain caused by endometriosis.
To provide clinical data on clinical efficacy to support embolisation of uterine fibroids using Embozene microsferes
To determine whether the introduction of a levonorgestrel-releasing intrauterine system (LNG-IUS) directly after endometrial ablation (EA) alleviates pain and heavy menstrual bleeding and reduces the need for subsequent hysterectomy compared with…