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Optimisation of cost effectiveness through Individualised FSH Stimulation dosages for IVF Treatment: The OPTIMIST trial.

To evaluate whether in an IVF program routine application of an ORT and a subsequent individualised FSH regimen is cost-effective compared to a standard dose regimen.

A Phase II Study to Evaluate: Delay in Intravaginal Ejaculatory Latency Time (IELT), Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Two Oral Doses of GSK557296 in a Randomized, Double Blind, Placebo-Controlled, Parallel Group Study in Men with Premature Ejaculation

To determine if an on demand dosing of 50 or 150 mg of GSK557296 demonstratessuperior efficacy with respect to duration of IELT during an 8 week study periodcompared to placebo in men with premature ejaculation.To assess safety and tolerability of…

Intracytoplasmatic Sperm Injection using testicular spermatozoa in men with azoospermia; an observational study with follow-up of the offspring.

To evaluate the efficacy of TESE and to describe the risks of the TESE procedure for the men with a four year follow-up of their offspring.

Treatment of Endometriosis with Epigallocatechin gallate:
a double-blind randomized placebo-controlled crossover pilot trial.

To evaluate if Epigallocatechin gallate (EGCG) is an effective treatment for pain in endometriosis patients using oral contraceptives by using Visual Analogue Scores (VAS) * To evaluate if the VAS pain scores are lower after EGCG versus placebo…

Sacrospinous ligament fixation versus Elevate Posterior procedure in treatment of primary apical prolapse stage * 2: a multi-center randomised controlled trial.

To compare the effects of Elevate Posterior procedure versus sacrospinous ligament fixation on pelvic floor function.

Oocyte vitrification in women at risk of ovarian failure; an observational study with follow-up of children

To determine safety of oocyte vitrification.

A randomized, double-blind, double-dummy, parallel- group, multi-center phase IIb study to assess the efficacy and safety of different dose combinations of an aromatase inhibitor and a progestin in an intravaginal ring versus placebo and leuprorelin / leuprolide acetate in women with symptomatic endometriosis over a 12-week treatment period

- The studymedication in this clinical study was developed for long-term use in patients with endometriosis associated pelvic pain to release the pain and to avoid to otherwise necessary operation.Primary objective-To assess the dose-response…

Sacrospinous ligament fixation combined with anterior colporrhaphy versus Elevate Anterior procedure in treatment of primary apical and anterior compartment prolapse stage >= 2: a multi-center randomised controlled trial.

To compare the effects of sacrospinous ligament fixation combined with anterior colporrhaphy versus Elevate Anterior procedure on pelvic floor function.

Subjective and objective outcome after laparoscopic sacrocolpopexy

The objective of the study is to evaluate the subjective and objective effectivity and safety of the laparoscopic sacrocolpopexy of 189 patients who underwent this procedure in the period August 2004 - December 2014 in the Diakonessenhuis Utrecht/…

Cognitive behavioral therapy to improve quality of life after surgical treatment of women with endometriosis

The primary objective of this study is to investigate whether usual care combined with CBT improves QoL in patients undergoing surgery for endometriosis compared to usual care only. Secondary objectives are to investigate whether pain intensity,…

Laparoscopic sterilization and diagnostic laparoscopy under general anesthesia or conscious sedation; a randomized controlled trial

Main objective is to determine whether patients have a better recovery after laparoscopic sterilization or a diagnostic laparoscopy under conscious sedation compared to general anesthesia as measured with the QoR-40 one day after surgery.

How much risk are female cancer survivors willing to take to get pregnant by autotransplantation of cryopreserved ovarian cortex tissue

Improving fertility preservation counseling by gynaecologists by providing more insight in important ascpects for patients regarding fertility preservation trough autotransplantation of cryopreserved ovarian tissue.

A randomized, placebo-controlled, double-blind, parallel-group, multi-center, exploratory dose-response study to assess the efficacy and safety of different oral doses of BAY1128688 in women with symptomatic endometriosis over a 12-week treatment period

Purpose of the study is to test whether study drug BAY1128688 brings relief for pain to women with endometriosis and if so to get a first impression which dose(s) work best.