145 results
This project aims to determine the validity of a home-based continuous bradykinesia assessment using free typing behaviour analysis. Secondarily, we aim to capture the presence of sequence effect in Parkinson's Disease patients using a computer…
Concordance between MET diagnosis with and without the use of ultrasound with the chart review definitive diagnosis will be studied. Also other secondary endpoints will be evaluated.
Objective: The primary objective of this study is to investigate whether pain experience decreases or increases when cognitive functions decline in patients with Parkinson's disease. Furthermore will be investigated whether this is influenced…
A. To gain more knowledge about the prevalence of TBI in male prisoners in the PPC and the relationship of TBI with violent crime and aggression. We expect that TBI is more common in violent offenders than in non-violent offenders. More specific, we…
[1] To develop robust assays for quantification of novel CSF/blood biomarkers of CAA.[2] To determine the contribution of CAA to cognitive decline in dementia and ICH patients, using CAA-specific biomarkers
The aim of this study is to investigate the effects of DMF (Tecfidera) on the association between fatigue and fatigability measures in pwRRMS starting with DMF medication.
To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.
Primary Objectives: * To determine if NA patients have altered cerebral activity related to motor planning of their affected arm compared to healthy controls and compared to their non-affected arm.* To determine if specific rehabilitation focused on…
Primary: - To evaluate the efficacy of 2 dose quantities of lasmiditan on migraine headache pain freedom compared to placebo - To evaluate the consistency of response to 2 dose quantities of lasmiditan compared to placeboSecondary: - To evaluate the…
This study aims to investigate the biological efficacy and safety of eculizumab in patients with aneurysmal SAH.
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
1. To study reproducibility of a qualitative scale for abnormality of brachial plexus MRI.2. To study usefulness of quantification of nerve size using maximum intensity projection techniques (MIP) , and compare results with HRUS of the brachial…
To determine the relationships between respiratory function, secretion management, RTIs and mortality in order to optimize medical decision-making.
1. To test the performance of the wearable SDD (Nightwatch) prospectively and the remote SDDs (video and audio) retrospectively in a family home setting. 2. To explore the feasibility of the Nightwatch
The primary objective of this study is to confirm that levosimendan can significantly improve respiratory function measured by supine slow vital capacity (SVC) in amyotrophic lateral sclerosis (ALS) patients.The secondary objective is to confirm…
This study has been transitioned to CTIS with ID 2024-513041-37-00 check the CTIS register for the current data. Primary objective of this study is to significantly reduce relevant (moderate/severe) parenchymatous brain injury on postoperative MRI…
The aim of this study is to combine measurements of the NDT with EEG recording and analysis to observe neurophysiological activity during nociceptive processing in CRPS patients. In this explorative study, multiple types of stimuli are delivered.…
To determine the diagnostic accuracy of dry electrode cap EEG for diagnosis of LVO-a, when performed by paramedics in the ambulance in patients with a suspected AIS.
Case series study (10 persons with epilepsy-related anxiety symptoms and/ or posttraumatic stress):-To examine the potential effects of EMDR therapy in terms of reducing anxiety, from pre-treatment to post-treatment. Randomized controlled trial (75…
The primary objective of Part 1 is the primary objective of the entire study.Part 1The primary objective of Part 1 is:* To evaluate the effect of ZX008 0.8 mg/kg/day versus placebo as adjunctive therapy for the treatment of uncontrolled seizures in…