35 results
The primary aim of this study is to evaluate the feasibility, clinical effectiveness and cost effectiveness of a caregiver mediated exercises programme combined with e-health services (CARE4STROKE+) to improve self-reported health status and reduce…
We aim to compare the effectiveness, feasibility and safety of both metformin and sitagliptin in patients with TIA or minor ischemic stroke and impaired glucose tolerance. Furthermore, we will assess whether a slow increase in dose of metformin over…
Primary Objective:- To evaluate the efficacy of PF-04360365 (ponezumab) in subjects with probableCAA as compared to placebo on a BOLD fMRI measure of cerebrovascularreactivity.Secondary Objectives:- To evaluate the efficacy of PF-04360365 (ponezumab…
To compare the feasibility and safety of surface cooling to 34, 34.5, and 35*C, started within 4.5 hours after the onset of acute ischaemic stroke and maintained for 24 hours, in awake patients on a stroke unit.
Primary: to determine whether an early psychological intervention poststroke in order to reduce symptoms of anxiety and depression, is feasible.Secondary: To evaluate if an early individual psychological intervention in patients independent in…
To find out if patients with secondary cerebral vasospasm after SAH can benefit from cervical TENS.
The objective of this study is to determine the clinical efficacy of endovascular thrombolytic treatment (ET) as compared to standard treatment (any therapeutic heparin regimen) in patients with proven cerebral venous sinus thrombosis and a high…
The main goal of this study is to evaluate the functional efficacy of the Actigait® system as a FES device, as well as its training effects with regard to (complex) walking. In addition, with regard to the training effects of FES, we intend to…
The study objective is to evaluate, with respect to hand function, the effect of a physical therapy program based on mirror therapy compared to conventional physical therapy in chronic stroke patients and to improve our understanding of the…
Firstly, to investigate whether the absolute magnitude of Platelet Inhibition inversely correlates with the number of TCD-detected microemboli during and after CAS in patients who are being pre-treated with either a 300 mg or a 600 mg loading dose…
To optimize a safe five-day intensive intravenous insulin treatment post stroke and to assess glucose profiles in patients with stroke and HG on admission, receiving standard continues enteral tube feeding.
The primary objective is to investigate the feasibility and the safety of heliox administration, a gaseous mixture of 79% helium en 21% oxygen, for 8 hours in acute ischemic stroke.
The objective of this study is to examine the influence of a single dose of fluoxetine and of movement observation on cortical activity, and to relate the changes of the activity of the brain to muscle activation, motor function and motor control in…
The aim of the present study is to increase the understanding of the optimal administration of mirror therapy and thereby improve the quality and effectiveness on this therapy. In order to realise this several different applications of mirror…
The objective of this trial is to investigate the feasibility and safety of helium ventilation post cardiac arrest.
- What are the effects of different types of ankle foot orthoses on weight-bearing and static and dynamic balance contribution of the paretic and non-paretic leg in stroke patients? - What are the effects of different types of ankle foot orthoses on…
Objective of this dose-escalation study with Lu AA24493 is to evaluate the safety, tolerability, immunogenicity and pharmacokinetics of multiple doses Lu AA 24493 in patients with acute ischemic stroke. In addition patient outcome on National…
To determine the instantaneous effects of cerebellar tDCS during PFT on posturographical and neurophysiological parameters in stroke patients and healthy subjects.
This study aims to investigate the biological efficacy and safety of eculizumab in patients with aneurysmal SAH.
This study has been transitioned to CTIS with ID 2025-520540-15-00 check the CTIS register for the current data. Primary Objective: To determine the safety and efficacy of 6000 IU C1-INH in patients with subarachnoid hemorrhage (SAH)Primary…