39 results
The primary aim of the proposed study is to assess whether stenting for symptomatic vertebral artery stenosis >= 50% is feasible and safe. A secondary aim is to assess the rate of new vascular events in the territory of the vertebrobasilar…
EXPLICIT aims tot obtain better functional outcome by early intensive rehabilitation. Next to clinical tests to measure improvement in function, neuroplasticity is assessed by fMRI, TMS and haptic robots. The combination of clinical outcome measures…
1. To determine the diagnostic accuracy, in terms of detecting a vascular malformation, of CTA, MRI/MRA, DSA, or combinations thereof in patients with ICH?2. To find out which test or combination of tests is most effective for the detection of…
Primary: - What are the effects of gait training with the gait rehabilitation device LOPES on the quality and ability of walking in chronic stroke patients with a stiff-knee gait?- What are the effects of two different training modes in the gait…
To assess the feasibility of a randomized clinical trial on induced hypertension, and to assess whether the studied intervention is effective in increasing CBF.
The aim of this study is to investigate the effect of a MSE intervention on social participation and quality of life in chronic stroke patients. This MSE intervention will be compared to a controlgroup in order to measure the additional effect of…
To find out if cervical TENS affects cerebral bloodflow as measured with transcranial doppler sonography in healthy subjects, and to find a dose-response relation for this effect. To find out if cervical TENS can suppress sympathetic tone as…
The objective of this study is to determine whether the dichotomization in good and poor outcome by the composite scale, corresponds better with the parents' and doctor's opinion on the outcome than the PSOM. The composite scale willl be…
The primary objective of the present study is to characterize the glucose metabolism in patients with SAH in the acute- and, sub acute phase and during follow-up. The secondary objectives are to relate glucose metabolism to clinical condition on…
The study should determine whether non-invasive continuous blood pressure values are comparable to intermittant oscillometric blood pressure determinations.
The purpose of this study is to investigate the acute effects of a single bout of WBV on spasticity of calf muscle in stroke patients.
The primary objective is to investigate the feasibility and the safety of heliox administration, a gaseous mixture of 79% helium en 21% oxygen, for 8 hours in acute ischemic stroke.
The objective of this study is to examine the influence of a single dose of fluoxetine and of movement observation on cortical activity, and to relate the changes of the activity of the brain to muscle activation, motor function and motor control in…
Studying whether the SWT or the aSWT is the most applicaple measuring tool to determine (maximal) exercise capacity in patient with stroke, by calculating the test-retest reliability and the validity.
The objective of the study is to assess whether in young patients with arteriopathic stroke perfusion abnormalities in non-infarcted brain are associated with the type and course of arteriopathy and stroke outcome in terms of functional recovery and…
The aim of this study is to invite a new cohort of CADASIL patients for a 7 Tesla MRI scan. By doing this, we aim to get more insight into the pattern and development of cortical atrophy and vessel wall thickening in CADASIL patients of different…
The primary aim of this study is to evaluate the added value of hemodynamics for multi-factorial rupture risk assessment of intracranial aneurysms. The secondary aim is to build a statistical model that can best predict aneurysm rupture taking into…
The primary objective of the study is to evaluate the efficacy of desmoteplase 90µg/kg versus placebo in terms of favourable outcome at Day 90 in subjects with acute ischemic stroke. Secondary objectives are to evaluate: the efficacy of desmoteplase…
Objective of this dose-escalation study with Lu AA24493 is to evaluate the safety, tolerability, immunogenicity and pharmacokinetics of multiple doses Lu AA 24493 in patients with acute ischemic stroke. In addition patient outcome on National…
to investigate the risk of death and incident cardiovascular diseaseto investigate the risk of mild cognitive impairment and incident (vascular) dementia