21 results
Objective: The aim of this comparative study is to identify the highest value-based practice for ruptured intracranial aneurysm patients in the short-, medium-, and long term by prospective registration.
Main objectives are:1. To explore differences in cerebral perfusion and flow pulsatility between CoA patients and controls.2. To quantify ischemic white matter lesions and cerebral microbleeds in CoA patients with comparison to controls.Secondary…
The aim of this study is to gauge the feasibility and potential order-of-magnitude the ReHab-TOAT concept may have on improving arm-hand skill performance in both subacute and chronic stroke patients. These data will be used to a) optimize the…
Primary objective:To investigate in Adolescent and Young Adult (AYA) Head and Neck Cancer (HNC) survivors treated with unilateral radiotherapy 5-10 years before, the long-term vascular complications in terms of carotid wall changes (ultrasonography…
The aim of this pilot study is to assess the feasibility of the use of CPAP in the acute phase of stroke in AIS patients. In other words, we want to evaluate if the treatment is tolerated and whether it can be applied as scheduled.
To explore the relation between (changes in) cerebrovascular function and the change in cognitive function in older adults with and without MCI across follow-up.
The goal of this study is to test the effectiveness of using the ArmAssist and Antari Homecare platform at home on upper extremity function in chronic stroke patients.Secundairy objectives are:- To evaluate the user-friendliness of the ArmAssist and…
To assess image quality of MR-STAT-generated synthetic image data sets in patients with neurological diseases (primary objective), and compare image quality of these synthetic images with those acquired individually according to standard clinical…
Primary objectiveTo investigate the efficacy of low dose colchicine (0.5mg/day) plus usual care (antiplatelet, lipid-lowering, antihypertensive treatment, and appropriate lifestyle advice) compared with usual care alone to prevent non-fatal…
The objective of this study is to test the feasibility, functionality and comfort of the AFO as an aid to regain the active RoM of the ankle joint in UMND patients with equinus foot. Results of the study will be used to further optimize the AFO…
This study has been transitioned to CTIS with ID 2024-514615-10-01 check the CTIS register for the current data. This study investigates the effectivity and the safety of deferoxamine use in patients with aneurysma subarachnoidhemorrhage.
To determine whether neglect training complemented with tACS treatment in chronic stroke patients suffering from neglect improves neglect-related symptoms compared to neglect training with sham stimulation.
To test the safety and preliminary efficacy of a dual acute thrombolytic treatment consisting of a small intravenous (IV) bolus of alteplase followed by IV infusion of m-pro-urokinase against usual treatment with IV alteplase in patients presenting…
To determine whether reactive gliosis persists >3 years after SAH and whether this response relates to cognitive impairment after SAH.
The primary objective of the present study is to assess the added values of using tele-rehabilitation services, combined with caregiver mediated exercises to improve the level of self-reported mobility at home. Secondary objectives are to assess the…
Aim and Objectives The overall aim is to define the broad disease spectrum of cysteine altering NOTCH3 mutations, specifically the as yet unexplored milder end of this spectrum, and to determine to what extent the mutation position predicts disease…
To develop a feasible assessment protocol to quantify the impaired upper extremity function in terms of muscle weakness, spasticity, synergy and viscoelastic properties around the elbow.To evaluate the reliability (test-retest, measurement error)…
The main objective of this study is to explore the accuracy of sCTA and ceMRA compared to DSA in the diagnosis of complete aneurysm occlusion in patients treated with a FD stent. In addition, we will look at accuracy of sCTA and ceMRA in…
In oral FXa inhibitor-treated patients with acute intracranial bleeding, the objectives of this study are as follows:Primary Efficacy Objective:• To evaluate the effect of andexanet versus usual care on the rate of effective hemostasis.Secondary…
Establish relationship between static and dynamic CA during general intravenous or inhalational anaesthesia.