453 results
Primary objective* To evaluate the efficacy of IAT in addition to BMM compaed to BMM alone in terms of favourable outcome at 90 days, defined as a modified Rankin score of 0-3, in patients with an acute ischemic stroke caused by basilar artery…
Primary objective is to investigate whether secondary deterioration after acute stroke is associated with CSD, infraslow activity, or epileptiform activity. Secondary objectives are (1) to assess the feasibility of continuous full-band EEG to…
The main aim of this proof-of-principle project is to explore whether 1) standardized conditions (physical tasks, cognitive tasks and a combination of both) differing in task difficulty are associated with distinct physiological responses…
Primary Objectives: - To determine which technique is most optimal for measuring vascular reactivity in CADASIL patientsSecondary Objectives: - To study CADASIL disease progression over a 17- year time frame - To determine the correlation between…
Primary Objective: To study arterial vessel wall abnormalities of the intracranial vessels (circle of Willis and its main branches and the moyamoya vessels) in patients with MMV in comparison with age- and sex-matched subjects without known…
The objective is to investigate how dementia affects processing of pain. More precisely, we aim to investigate how dementia-related neurodegeneration (occurring in Alzheimer disease (AD), frontotemporal dementia (FTD) and vascular dementia (VD))…
POTENTIAL will be the first phase II RCT to assess the effects of combined cerebellar tDCS and VR-PFT in terms of outcomes at the level of body functions, activities and participation, as well as brain reorganization post stroke. Ultimately,…
Primary Objective: To assess the difference in prevalence of pituitary dysfunction between patients with and patients without fatigue after ischemic stroke. Secondary Objectives: 1. To assess the time course of pituitary dysfunction after ischemic…
The main research question is to compare the diagnostic accuracy of 7T MRI for cerebral vasculitis, with the standard diagnostic practice (SDP). The true nature of the disease will be assessed for all patients at the end of the study by re-…
For the reliability part, our objective to have an initial understanding of the validity of the DynMetrics measurement system when compared to the Vicon system (gold standard). For the usability part, our objective is to quantify the usability of…
To explore whether wearing the orthosis improves the performance of functional activities, additionally to obtain insight in the usability of the orthosis.
To examine the impact of remote ischaemic postconditioning after an ischaemic stroke on infarct size and clinical outcome in patients, but also to better understand the potential underlying mechanisms contributing to these effects.
1. To investigate the feasibility of controlling an arm- and hand support system with EMG, voice or wink control.2. To assess usability of the arm and hand support controlled by EMG, voice or wink.3. To investigate the possibility to distinguish…
Primary Objective: To verify the main effect of TDCS on brain excitability and the interaction effects of BDNF genotype and APLM latency on this main effect. Secondary Objectives: Compare different prediction models for the main effect of TDCS in a…
The primary objective is to gain insight into gaze behaviour of stroke survivors during upper extremity movements.
The aim of the present study is to gain more insight into the etiologies of post-stroke depression (PSD), post-stroke apathy (PSA), vascular cognitive impairment (VCI), and post-stroke dementia. Therefore, the primary objectives are to identify…
In a cohort of people after a minor stroke, we aim to investigate whether aforementioned balance tests are sensitive enough to detect subtle balance impairments. Secondly, we will investigate whether fall rates differ between people after a minor…
Primary Objective: to investigate the validity and reproducibility of the ST for measurement of cardiopulmonary capacity in stroke survivors. Secondary Objective(s): To establish 1. the reproducibility of the exercise time during the ST, 2. safety…
Our research aim is fourfold:1) We aim to assess the effect of hypertension on functional and structural markers of the brain using 3 tesla (T) and 7T MRI in patients who are temporary drug naïve and will be switched-on to medication as part of…
To investigate the feasibility of a 10 week (maximum) gait training with DFES in rehabilitation starting in the sub-acute phase after stroke and the initial efficacy on the recovery of spatiotemporal parameters, gait kinetics and kinematics,…