28 results
To determine the feasibility of rs-fMRI in neonates undergoing a planned diagnostic MRI session following perinatal asphyxia. To assess intra-session reproducibility (test-retest reliability) of the rs-fMRI technique in neonates with asphyxia.
Primary objective of this study is to assess the reliability and validity of the neuromuscular parameters of ankle joint impedance estimated by nonlinear SIPE technology in children with CP compared to current clinical manual tests and gait analysis…
Primary Objective: to derive iPSCs from patients with a variety of diseases caused by genetic mutations or genetic predisposition to disease or of unknown origin. The cells will be propagated and differentiated into a variety of somatic cell types…
1. Discribe the normal development of mastication in healthy children aged between 6 and 48 months by using the Mastication Observation and Evaluation (MOE). Which oral motor behaviours occurs?2. Determine the differences in mastication between…
Primary objective is to assess the reliability and assess the reliability and construct validity of the Repetitive Movement Test (RMT) as a measure of spasticity in children with CP scheduled for ITB treatment, between 6-18 year.
Using a variety of methods, we try to determine the dynamics of the chewing movements in typically developing children and children with CP. The methods are, in some degree, complementary to each other. Given the limitations of the methods we need…
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
The aim of this research is to study the MRI-sequence with the best parameter settings for the most optimal image quality to visualize the sacral plexus and its branching nerves. Diffusion-weighted imaging, diffusion tensor imaging, 3D-GE-MEDIC and…
The aim of this study is to visualize the cervical roots and brachial plexus in neonates reliably and reproducable.
Applicability of fetal brain imaging techniques for clinical purposes.
The primary objective of this study is to determine whether 3D kinematics, kinetics and spatiotemporal parameters during walking on the V-Gait system are comparable to overground walking in children with cerebral palsy and in healthy children…
The aims of the study are 1) to upgrade an existing GA protocol based on inertial system(developed at the INAIL Prostheses Centre in collaboration with the University of Bologna) in terms offinding out which calibration procedures result suitable to…
To optimize the 3D ultrasound reconstruction and dynamometer as a clinical tool for measurement of morphological and mechanical muscle properties, and to compare the m .gastrocnemius medialis of healthy children to the m .gastrocnemius medialis of…
Aim of this project is to diagnose hearing impairment, and underlying disorders in speech perception and production, and to develop and implement adequate intervention techniques, which are subsequently evaluated. The ultimate goal is to prevent…
1. The development of a standardized screeningsinstrument to evaluate the language comprehension of severly handicapped children with movement disorders and who cannot speak, as a result of white matter damage.2.To evaluate the difference between…
To determine to what extent dynamic spasticity can be recognized and quantified in the gait pattern of children with spastic CP and to develop a meaningful and (clinically) applicable measure of dynamic spasticity
The main goal of the VUmc part of the study is to acquire sets of data related to Neurological and Neuromuscular Diseases; in order to build a paediatric digital repository and to develop biophysical modelling and probabilistic modelling.
1- to describe the presence and severity of hemiplegic CP on the basis of neonatal MRI findings and correlate the involvement of different structures (basal ganglia, posterior limb of the internal capsule and hemisphere) with the size of the lesion2…
To examine the intra-rater reliability and validity of the paediatric DDA.
To assess in moderate preterm infants:1) The prevalence and characteristics of brain injury; 2) The relation between perinatal factors and brain injury;3) The validity of cUS for detection of brain injury as compared to MRI (considered the golden…