40 results
To determine the feasibility of rs-fMRI in neonates undergoing a planned diagnostic MRI session following perinatal asphyxia. To assess intra-session reproducibility (test-retest reliability) of the rs-fMRI technique in neonates with asphyxia.
Primary objective of this study is to assess the reliability and validity of the neuromuscular parameters of ankle joint impedance estimated by nonlinear SIPE technology in children with CP compared to current clinical manual tests and gait analysis…
We hypothesize that functional brain network measures may serve as a marker for (disrupted) neurodevelopment in very preterm born infants. Objective: we propose to perform two studies aiming to answer the following questions.Phase 1: Retrospective…
In this study one of the goals is to compare 7 tesla MRI with 3 tesla MRI in terms of lesion detection in epilepsy patients and depiction of specific dysplasia-related imaging characteristics. Furthermore, resected tissue will be scanned ex-vivo at…
Primary Objective: to derive iPSCs from patients with a variety of diseases caused by genetic mutations or genetic predisposition to disease or of unknown origin. The cells will be propagated and differentiated into a variety of somatic cell types…
1. Discribe the normal development of mastication in healthy children aged between 6 and 48 months by using the Mastication Observation and Evaluation (MOE). Which oral motor behaviours occurs?2. Determine the differences in mastication between…
Primary objective is to assess the reliability and assess the reliability and construct validity of the Repetitive Movement Test (RMT) as a measure of spasticity in children with CP scheduled for ITB treatment, between 6-18 year.
Using a variety of methods, we try to determine the dynamics of the chewing movements in typically developing children and children with CP. The methods are, in some degree, complementary to each other. Given the limitations of the methods we need…
To establish benchmark values in healthy control fetuses, to compare these with our cohort of fetuses with severe CHD.
The objective of this study is to measure the stiffness of the elbow as a measure for axonal misrouting. This method can later aid physicians in determining whether to use botulinum A or not in OBPL.
The aim of this research is to study the MRI-sequence with the best parameter settings for the most optimal image quality to visualize the sacral plexus and its branching nerves. Diffusion-weighted imaging, diffusion tensor imaging, 3D-GE-MEDIC and…
The aim of this study is to visualize the cervical roots and brachial plexus in neonates reliably and reproducable.
Applicability of fetal brain imaging techniques for clinical purposes.
The primary objective of this study is to determine whether 3D kinematics, kinetics and spatiotemporal parameters during walking on the V-Gait system are comparable to overground walking in children with cerebral palsy and in healthy children…
The primary objective of the study is to assess (acute) brain injury in the perioperative phase by cerebral MRI in infants with non-cardiac congenital anomalies requiring surgery in the neonatal period.
The primary goal of this study is to evaluate the clinical long term results of patients with a forearm osteotomy and/or soft-tissue procedures to correct a supination deformity. Furthermore we will try to identify association between functional…
Objective #1: Implement clinical platform. We see the need to implement a clinical platform for two purposes. First, we want to design a biomarker profile of perinatal brain damage in human newborns (see above). Thus, we have established a…
The aims of the study are 1) to upgrade an existing GA protocol based on inertial system(developed at the INAIL Prostheses Centre in collaboration with the University of Bologna) in terms offinding out which calibration procedures result suitable to…
The objective of this research is to find out to what extent a correlation exists between axonal misrouting, the extent of the injury and the associated functional recovery.
To optimize the 3D ultrasound reconstruction and dynamometer as a clinical tool for measurement of morphological and mechanical muscle properties, and to compare the m .gastrocnemius medialis of healthy children to the m .gastrocnemius medialis of…