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Neurological signs in very high-risk infants and developmental outcome at school age

To improve prediction of neurological and functional outcome at school age in infants at high risk of cerebral palsy.

Biomarkers for outcome at school age in preterm born children

The objective of the study is to identify biomarkers that associate to brain (physiological) status or mental (functional) health status and their interaction. More specific, our first aim is to determine the association between neuroinflammatory…

Effect of ALlopurinol in addition to hypothermia for hypoxic-ischemic Brain Injury on Neurocognitive Outcome - a blinded randomized placebo controlled parallel group multicenter trial for superiority (Phase III)

This study has been transitioned to CTIS with ID 2024-511322-31-00 check the CTIS register for the current data. To evaluate whether in newborns with asphyxia and early clinical signs of hypoxic ischemic encephalopathy, early postnatal allopurinol…

Preterm brain injury, long-term outcome and brain development study

To investigate the association between preterm brain injury, impaired brain development and neurodevelopmental outcomes 9-10 years after VPT birth

Cerebral injury after neonatal cardiac surgery: Outcome at school age

To gain insight in the cerebral consequences of neonatal cardiac surgery.