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Partial sleep deprivation in long-term video-EEG monitoring

To assess the provoking effect of partial sleep deprivation on paroxysmal neurological events in a EMU setting, in people with possible epileptic seizures.

Promoting implementation of seizure detection devices in epilepsy care: the PROMISE study

1. To test the performance of the wearable SDD (Nightwatch) prospectively and the remote SDDs (video and audio) retrospectively in a family home setting. 2. To explore the feasibility of the Nightwatch

Epilepsy and anxiety- targeting a vicious cycle:
Comparison of cognitive behavioural therapy (CBT), eye movement desensitization and reprocessing (EMDR) therapy and wait-list in targeting epilepsy-related anxiety and posttraumatic stress

Case series study (10 persons with epilepsy-related anxiety symptoms and/ or posttraumatic stress):-To examine the potential effects of EMDR therapy in terms of reducing anxiety, from pre-treatment to post-treatment. Randomized controlled trial (75…

A Two-Part Study of ZX008 in Children and Adults with Lennox-Gastaut Syndrome (LGS); Part 1: A Randomized, Double-blind, Placebo-controlled Trial of Two Fixed Doses of ZX008 (Fenfluramine Hydrochloride) Oral Solution as Adjunctive Therapy for Seizures in Children and Adults with LGS, Followed by Part 2: An Open-label Extension to Assess Long-Term Safety of ZX008 in Children and Adults with LGS.

The primary objective of Part 1 is the primary objective of the entire study.Part 1The primary objective of Part 1 is:* To evaluate the effect of ZX008 0.8 mg/kg/day versus placebo as adjunctive therapy for the treatment of uncontrolled seizures in…

Rolandic Care Program

The overall aim of this study is to identify developmental deficits in children with Rolandic epilepsy. If developmental deficits are observed, we hope to determine timing, persistence, and prognostic factors for developmental deficits and improve…

A multicenter, open-label, parallel-group study in study participants with epilepsy to evaluate the effect of oxcarbazepine on the pharmacokinetics, safety, and tolerability of padsevonil.

The primary objective of this study is to evaluate the effect of stable coadministered OXC (as monotherapy or adjunctive therapy) on the PK of PSL in study participants with epilepsy compared with study participants co-medicated with stable doses of…