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The effect of cognitive rehabilitation therapy and mindfulness based cognitive therapy on cognitive functioning in multiple sclerosis.

The main aim of the current study is to investigate whether two promising therapies, namely cognitive rehabilitation therapy (CRT) and mindfulness based cognitive therapy (MBCT), may improve cognitive functioning of patients with MS. Additionally,…

Are alpha blockers effective in the treatment of bladder elimination problems in female patients with Multiple Sclerosis?

Improves the alpha blocker Silodosin the bladder emptying in patients with MS? Improves the alpha blocker Silodosin the quality of life of patients with MS?

Cognitive impairment in Multiple Sclerosis: Investigating the temporal dynamics of functional reorganization, cognition, and the susceptibility to change after cognitive rehabilitation

The aim of the proposed study is to obtain insight into the temporal dynamics of functional reorganization and cognition, and to assess the effect of cognitive rehabilitation on this adaptive mechanism and cognitive functioning.

Need for speed: a pilot study on feasibility of cognitive rehabilitation for patients with progressive multiple sclerosis (MS)

The aim of this pilot study is to investigate the feasibility and to gain preliminary information on the effectiveness of a cognitive rehabilitation program in patients with (severe) progressive MS, i.e. a speed of processing training (SPT).…

An open-label study to evaluate the efficacy and safety of ocrelizumab in patients with relapsing remitting multiple sclerosis who have a suboptimal response to an adequate course of disease-modifying treatment

This study will evaluate the efficacy and safety of ocrelizumab in patients with relapsing remitting multiple sclerosis (RRMS) who have a suboptimal response to an adequate course of a disease modifying treatment (DMT).

Randomized, double blind, placebo- and active comparator- controlled 3-way crossover study in healthy subjects to assess the safety, tolerability, pharmacokinetics and pharmacodynamics of ENX-201

To assess PK of MPhs and MP.