42 results
Primary Objectives: To formulate answers to the following questions:Three main study objectives will be examined in the present project.1. What are the employed coping strategies in patients with refractory epilepsy and how do these develop over…
The purpose of this research project is to improve the overall quality and resolution of the MRI images, to correct for movement effects during the procedure and to speed up the investigation. The goal is to enhance and standardize a technique…
Primary objective:1. To investigate the clinical value of [18F]Flutemetamol PET in memory clinic patients and especially those with suspicion of young onset dementia in terms ofa. change in (level of confidence of) diagnosis;b. impact on patient…
To develop and examine the test-retest reliability of a wheelchair skills test for children
In PD patients: To investigate the effect of Levodopa on postural responses after translational perturbations. These outcomes will be helpful to decide whether patients in the cohort study should be measured in the ON or OFF medication state. In…
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
Discrimination of probable AD patients from healthy volunteers by ZK 6032924 PET imaging as evaluated by visual analysis of the brain distribution patterns and by SUV values in probable AD patients as compared to healthy volunteers for brain imaging…
To examine neurocognition in 100 HIV1 seropositive patients on chronic effective cART using three different tests: the Montreal cognitive assessment (MoCA) , the International Aids Dementia scale (ADS) and extensive neuropsychological testing of…
The main object of this study is:Optimization of the face-name association task, such that this task can be used to examine the prediction of postoperative memory failure in preoperative patients with epilepsy.Sub Objectives:- Investigation and…
To investigate whether stress (chronic and acute) influences cognitive functioning in PD.
In the present study, we aim to estimate concordance between two biomarkers developed to interrogate the presence of brain amyloid deposition. This includes a new amyloid PET-tracer, [18F]Flutemetamol, and a CSF biomarker The objective of the…
The mean objective of this research project is the implementation in daily clinical practice of MEG as the examination of the first choice for the diagnosis of patients with suspicion of epilepsy. Furthermore, the current project links directly to…
The aim of this study is to evaluate the prevalence and character of NDE in patients treated with hypothermia after CPR.
The primary objective of this study is to investigate whether a data-driven fMRI procedure enables the identification of the epileptiform network that can be used in the pre-operative work-up of patients with localization related epilepsy.
We need objective and validated tests for the assessment of the severity of impairment in CFS/ME patients. In 2 areas these tests will be essential: for studies of the effect of interventions and for the assessment of disability.Hardly any research…
- To assess the usefulness of 5-HT phMRI (BOLD-, PWI and ASL based phMRI) in assessing cerebral 5-HT neurotoxicity when compared to SERT SPECT.- To assess which MRI technique (BOLD-, PWI or ASL) is best in assessing cerebral 5-HT neurotoxicity when…
OBJECTIVES: -to assess the usefulness of DA-phMRI (task related fMRI, steady state fMRI and ASL based phMRI) in assessing amphetamine induced DA-neurotoxicity when compared to DAT SPECT.-to assess which MRI technique (task related fMRI, steady state…
Our working hypothesis is based on the interplay between vascular dysregulation, neuropathological alterations and decline in AD brain function. In the latent phase vascular dysregulation is already apparent when patients are asymptomatic.…
To dermine the reliability of the newly proposed diagnsotic criteria.
1) determine the level of NSE with a 100% certain predictive value for poor outcome in patients treated with hypothermia after CPR; 2) investigate relationships between SSEP during and after hypothermia; 3) Confirm the results of the PROPAC study,…