44 results
Discrimination of probable AD patients from healthy volunteers by ZK 6032924 PET imaging as evaluated by visual analysis of the brain distribution patterns and by SUV values in probable AD patients as compared to healthy volunteers for brain imaging…
To examine neurocognition in 100 HIV1 seropositive patients on chronic effective cART using three different tests: the Montreal cognitive assessment (MoCA) , the International Aids Dementia scale (ADS) and extensive neuropsychological testing of…
The primary aim of the proposed multi-site study will be to determine internal and external validity of the proposed new diagnostic criteria.
To dermine the reliability of the newly proposed diagnsotic criteria.
- To assess the usefulness of 5-HT phMRI (BOLD-, PWI and ASL based phMRI) in assessing cerebral 5-HT neurotoxicity when compared to SERT SPECT.- To assess which MRI technique (BOLD-, PWI or ASL) is best in assessing cerebral 5-HT neurotoxicity when…
OBJECTIVES: -to assess the usefulness of DA-phMRI (task related fMRI, steady state fMRI and ASL based phMRI) in assessing amphetamine induced DA-neurotoxicity when compared to DAT SPECT.-to assess which MRI technique (task related fMRI, steady state…
In the proposed project we aim to predict falls in daily life and to identify both aging- and disease-related impairments that underlie impaired postural control and an increased risk of falling in daily life.
Primary objective:1. To investigate the clinical value of [18F]Flutemetamol PET in memory clinic patients and especially those with suspicion of young onset dementia in terms ofa. change in (level of confidence of) diagnosis;b. impact on patient…
The primary objective of this study is to investigate whether a data-driven fMRI procedure enables the identification of the epileptiform network that can be used in the pre-operative work-up of patients with localization related epilepsy.
The mean objective of this research project is the implementation in daily clinical practice of MEG as the examination of the first choice for the diagnosis of patients with suspicion of epilepsy. Furthermore, the current project links directly to…
We need objective and validated tests for the assessment of the severity of impairment in CFS/ME patients. In 2 areas these tests will be essential: for studies of the effect of interventions and for the assessment of disability.Hardly any research…
Our working hypothesis is based on the interplay between vascular dysregulation, neuropathological alterations and decline in AD brain function. In the latent phase vascular dysregulation is already apparent when patients are asymptomatic.…
The main aim of the study is therefore to examine mu wave activity during observation, execution of movements and during movement imagery in comparison to a passive resting state and active relaxation condition in stroke patients and matched healthy…
The purpose of the study is to assess the quantitative accuracy of the experimental HRRT PET scanner and to assess the potential benefits of high resolution PET.
1) determine the level of NSE with a 100% certain predictive value for poor outcome in patients treated with hypothermia after CPR; 2) investigate relationships between SSEP during and after hypothermia; 3) Confirm the results of the PROPAC study,…
To investigate whether stress (chronic and acute) influences cognitive functioning in PD.
The aim of this study is to evaluate the prevalence and character of NDE in patients treated with hypothermia after CPR.
This pilot study aims to investigate the retina, macula and optic nerve head with Optical Coherence Tomography (OCT) in AD patients in order to identify a neurodegenerative signature of AD in the eye. With Fundus Autofluorescence (FAF), amyloid…
The study's objective is to create an fMRI-reference database in order to make neuroscientific knowledge easily applicable and accessible to the clinic.
Translation of [18F]-MC22518 to the clinic to measure P-gp function in healthy volunteers.