14 results
The main objective is to determine the change in CS parameters upon administration of tapentadol in comparison to pregabalin in patients suffering from chronic pain that has a visceral or deep somatic origin.
This study has been transitioned to CTIS with ID 2023-507906-15-00 check the CTIS register for the current data. This study is designed to collect long-term safety, tolerability, effectiveness and health outcomes data in RMS patients.COVID-19…
Primary Objective: To determine if the (change in) gut and oral microbiome at baseline or in the first 3 months after start of Cladribine is a predictor for treatment response in subjects with active relapsing remitting MS.The secondary objectives…
The aim of this study is to evaluate the additional value of quantitative amyloid imaging analysis for modelling and assessing Alzheimer*s Disease (AD) dementia risk in individuals without dementia, compared to a range of existing cognitive, imaging…
MOPEAD will compare the four different subpopulations with regard to detection of hidden cases of mild cognitive impairment (MCI) due to AD or mild AD dementia using an extensive evaluation of selected individuals using cognition, biomarkers, and…
We hypothesize that synchronous tACS in the theta range will cause an enhancement of fronto-parietal brain synchronization and improvement in EF of MCI patients.We aim to apply tACS in the theta range over the left frontal and parietal areas of…
1. To determine the feasibility of performing a few functional magnetic resonance imaging (fMRI) tasks and clinical neurophysiological measurements in patients with mild to moderate AD.2. To validate the visual perception fMRI task in healthy…
Primary objectiveTo determine the efficacy of chronic treatment with arimoclomol 1200 mg/day (400 mg TID) compared to placebo over 76 weeks in subjects with ALS as assessed with Combined Assessment of Function and Survival (CAFS).Secondary…
Effect of hyperbaric oxygen therapy (HBOT) on patients with chronic neurological deficiency due to stroke.
• To determine the profile of CNS effects at several time points after 2 mg and 4 mg biperiden in comparison to placebo in healthy elderly subjects.• To investigate the safety and tolerability of biperiden in healthy elderly subjects.• To determine…
Objectives of the study are:- To investigate the difference in the nature and severity of objective visual disorders between patients with MS or PD who report visual complaints and those who do not report visual complaints.- To investigate the…
Investigation of the effect of an LPS challenge on:1. Nociceptive pain thresholds (primary endpoint);2. The expression of cell surface markers related to pain responses;3. Soluble markers related to painExploration of LPS effects on state-of-the-art…
Assessment of emotion recognition in patients who suffered an ischemic cerebellar stroke in the past 3 years.
Do neonatal critically ill children aged 9-16 years have problems with visuomotor integration? If yes, which aspects of the visuomotor integration are affected and require a possible intervention?